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1 Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans
Long Lin, Mette K. Andersen, Frederik Filip Stæger, Zilong Li, Kristian Hanghøj, Allan Linneberg, Niels Grarup, Marit Eika Jørgensen, Torben Hansen^📨, Ida Moltke^📨 & Anders Albrechtsen^📨
Genome Med 16, 71 (2024).

2 Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations.
Xiaodong Liu* , Long Lin* , Mikkel-Holger S. Sinding* , Laura D. Bertola, Kristian Hanghøj, Liam Quinn, Genís Garcia-Erill, Malthe Sebro Rasmussen, Mikkel Schubert, Patrícia Pečnerová, Renzo F. Balboa, Zilong Li, Michael P. Heaton, Timothy P. L. Smith, Rui Resende Pinto, Xi Wang, Josiah Kuja, Anna Brüniche-Olsen, Jonas Meisner, Cindy G. Santander, Joseph O. Ogutu, Charles Masembe, Rute R. da Fonseca, Vincent Muwanika, Hans R. Siegismund, Anders Albrechtsen^📨, Ida Moltke^📨, Rasmus Heller^📨
Nature Communications 15, 2921 (2024)

3 Giraffe lineages are shaped by major ancient admixture events
Laura D. Bertola* , Liam Quinn* , Kristian Hanghøj* , Genís Garcia-Erill, Malthe Sebro Rasmussen, Renzo F. Balboa, Jonas Meisner, Thomas Bøggild, Xi Wang, Long Lin, Casia Nursyifa, Xiaodong Liu, Zilong Li, Mumbi Chege, Yoshan Moodley, Anna Brüniche-Olsen, Josiah Kuja, Mikkel Schubert, Morris Agaba, Cindy G. Santander, Mikkel-Holger S. Sinding, Vincent Muwanika, Charles Masembe, Hans R. Siegismund, Ida Moltke ^📨 , Anders Albrechtsen ^📨, Rasmus Heller ^📨,
Current Biology,2024

4 African bushpigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival
Balboa* , Bertola* , Brüniche-Olsen* , … Moltke ^📨, Albrechtsen ^📨, Heller ^📨;
Nature Communications 15, 172 (2024)

5 Estimating admixture pedigrees of recent hybrids without a contiguous reference genome
Genís Garcia-Erill^📨, Kristian Hanghøj, Rasmus Heller, Carsten Wiuf, Anders Albrechtsen
Mol Ecol Resour 23(7) 2023

6 Evaluation of population structure inferred by principal component analysis or the admixture model.
Jan van Waaij* ^📨, Song Li* , Genís Garcia-Erill* , Anders Albrechtsen, Carsten Wiuf^📨;
Genetics: 2023, 225(2);

7 Fast and accurate out-of-core PCA framework for large scale biobank data.
Zilong Li^📨, Jonas Meisner, Anders Albrechtsen^📨
Genome Res: 2023, 33(9);1599-1608

8 A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland
Anne Cathrine Baun Thuesen* , Frederik Filip Stæger* , …, Anders Albrechtsen^📨, Ida Moltke^📨, Torben Hansen^📨
Lancet Reg Health Eur: 2023, 24;100529

9 An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention
Emil Jørsboe, Mette K Andersen,…, Ida Moltke^📨, Anders Albrechtsen^📨, Torben Hansen^📨
HGG Adv: 2022, 3(4);100118

10 Haplotype and population structure inference using neural networks in whole-genome sequencing data.
Jonas Meisner^📨, Anders Albrechtsen
Genome Res: 2022, 32(8);1542-52

11 Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.
Mette K Andersen* , Line Skotte* , Emil Jørsboe* ,…,Ida Moltke^📨, Torben Hansen^📨, Anders Albrechtsen^📨
Gastroenterology: 2022, 162(4);1171-1182.e3

12 Population genomics of the muskox’ resilience in the near absence of genetic variation
Pečnerová P.; Lord E.; Garcia-Erill G.; Hanghøj K.; Rasmussen M.S.; Meisner J.; Liu X.; van der Valk T.; Santander C.G.; Quinn L.; Lin L.; Liu S.; Carøe C.; Dalerum F.; Götherström A.; Måsviken J.; Vartanyan S.; Raundrup K.; Al-Chaer A.; Rasmussen L.; Hvilsom C.; Heide-Jørgensen M.P.; Sinding M.-H.S.; Aastrup P.; Van Coeverden de Groot P.J.; Schmidt N.M.; Albrechtsen A.; Dalén L.; Heller R.; Moltke I.; Siegismund H.R.
Mol. Eco.(2023)

13 Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives
Senftleber N.K.; Ramne S.; Moltke I.; Jørgensen M.E.; Albrechtsen A.; Hansen T.; Andersen M.K.
Appl Clin Genet(2023)

14 Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing
Gul R.; Firasat S.; Schubert M.; Ullah A.; Peña E.; Thuesen A.C.B.; Hussain M.; Staeger F.F.; Gjesing A.P.; Albrechtsen A.; Hansen T.
Front. genet(2023)

15 GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
Senftleber N.K.; Andersen M.K.; Jørsboe E.; Stæger F.F.; Nøhr A.K.; Garcia-Erill G.; Meisner J.; Santander C.G.; Balboa R.F.; Gilly A.; Bjerregaard P.; Larsen C.V.L.; Grarup N.; Jørgensen M.E.; Zeggini E.; Moltke I.^📨; Hansen T.^📨; Albrechtsen A.^📨
EJHG(2023)

16 Colonialism in South Africa leaves a lasting legacy of reduced genetic diversity in Cape buffalo
Quinn L.; Garcia-Erill G.; Santander C.; Brüniche-Olsen A.; Liu X.; Sinding M.-H.S.; Heaton M.P.; Smith T.P.L.; Pečnerová P.; Bertola L.D.; Hanghøj K.; Rasmussen M.S.; de Jager D.; Siegismund H.R.; Albrechtsen A.^📨; Heller R.^📨; Moltke I.^📨
Mol. Eco.(2023)

17 Polygenic heterogeneity in antidepressant treatment and placebo response
Nøhr A.K.; Forsingdal A.; Moltke I.; Howes O.D.; Vitezic M.; Albrechtsen A.; Dalby M.
Transl. Psychiatry(2022)

18 Warthog Genomes Resolve an Evolutionary Conundrum and Reveal Introgression of Disease Resistance Genes
Garcia-Erill G.; Jørgensen C.H.F.; Muwanika V.B.; Wang X.; Rasmussen M.S.; De Jong Y.A.; Gaubert P.; Olayemi A.; Salmona J.; Butynski T.M.; Bertola L.D.; Siegismund H.R.; Albrechtsen A.; Heller R.
Mol Biol Evol(2022)

19 Joint identification of sex and sex-linked scaffolds in non-model organisms using low depth sequencing data
Nursyifa C.* ; Brüniche-Olsen A.* ; Garcia-Erill G.; Heller R.^📨; Albrechtsen A.^📨
Mol. Eco. res(2022)

20 Estimation of site frequency spectra from low-coverage sequencing data using stochastic EM reduces overfitting, runtime, and memory usage
Rasmussen M.S.; Garcia-Erill G.; Korneliussen T.S.; Wiuf C.; Albrechtsen A.
Genetics(2022)

21 Efficient approaches for large-scale GWAS with genotype uncertainty
Jørsboe E.; Albrechtsen A.
G3(2022)

22 Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic
Duncan C.J.A.; Skouboe M.K.; Howarth S.; Hollensen A.K.; Chen R.; Børresen M.L.; Thompson B.J.; Stremenova Spegarova J.; Hatton C.F.; Stæger F.F.; Andersen M.K.; Whittaker J.; Paludan S.R.; Jørgensen S.E.; Thomsen M.K.; Mikkelsen J.G.; Heilmann C.; Buhas D.; Øbro N.F.; Bay J.T.; Marquart H.V.; Teresa de la Morena M.; Klejka J.A.; Hirschfeld M.; Borgwardt L.; Forss I.; Masmas T.; Poulsen A.; Noya F.; Rouleau G.; Hansen T.; Zhou S.; Albrechtsen A.; Alizadehfar R.; Allenspach E.J.; Hambleton S.; Mogensen T.H.
JEM(2022)

23 A large-scale genome-wide gene expression analysis in peripheral blood identifies very few differentially expressed genes related to antidepressant treatment and response in patients with major depressive disorder
Nøhr A.K.; Lindow M.; Forsingdal A.; Demharter S.; Nielsen T.; Buller R.; Moltke I.; Vitezic M.; Albrechtsen A.
Neuropsychopharmacology(2021)

24 Predictors and trajectories of treatment response to SSRIs in patients suffering from PTSD
Nøhr A.K.; Eriksson H.; Hobart M.; Moltke I.; Buller R.; Albrechtsen A.; Lindgreen S.
Psychiatry Res(2021)

25 The genetic history of Greenlandic-European contact
Waples R.K.; Hauptmann A.L.; Seiding I.; Jørsboe E.; Jørgensen M.E.; Grarup N.; Andersen M.K.; Larsen C.V.L.; Bjerregaard P.; Hellenthal G.; Hansen T.^📨; Albrechtsen A.^📨; Moltke I.^📨
Current Biology(2021)

26 Vicariance followed by secondary gene flow in a young gazelle species complex
Garcia-Erill G.; Kjær M.M.; Albrechtsen A.; Siegismund H.R.; Heller R.
Mol. Eco.(2021)

27 Detecting selection in low-coverage high-throughput sequencing data using principal component analysis
Meisner J.; Albrechtsen A.; Hanghøj K.
BMC Bioinformatics(2021)

28 High genetic diversity and low differentiation reflect the ecological versatility of the African leopard
Pečnerová P.; Garcia-Erill G.; Liu X.; Nursyifa C.; Waples R.K.; Santander C.G.; Quinn L.; Frandsen P.; Meisner J.; Stæger F.F.; Rasmussen M.S.; Brüniche-Olsen A.; Hviid Friis Jørgensen C.; da Fonseca R.R.; Siegismund H.R.; Albrechtsen A.; Heller R.; Moltke I.; Hanghøj K.
Current Biology(2021)

29 Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers
Schnurr T.M.; Jørsboe E.; Chadt A.; Dahl-Petersen I.K.; Kristensen J.M.; Wojtaszewski J.F.P.; Springer C.; Bjerregaard P.; Brage S.; Pedersen O.; Moltke I.; Grarup N.; Al-Hasani H.; Albrechtsen A.; Jørgensen M.E.; Hansen T.
Diabetologia(2021)

30 A reference-free approach to analyse RADseq data using standard next generation sequencing toolkits
Heller R.; Nursyifa C.; Garcia-Erill G.; Salmona J.; Chikhi L.; Meisner J.; Korneliussen T.S.; Albrechtsen A.
Mol. Eco. res(2021)

31 Large-scale inference of population structure in presence of missingness using PCA
Meisner J.; Liu S.; Huang M.; Albrechtsen A.
Bioinformatics(2021)

32 NGSremix: A software tool for estimating pairwise relatedness between admixed individuals from next-generation sequencing data
Nøhr A.K.; Hanghøj K.; Garcia-Erill G.; Li Z.; Moltke I.; Albrechtsen A.
G3(2021)

33 Evaluation of model fit of inferred admixture proportions
Garcia-Erill G.; Albrechtsen A.
Mol. Eco. res(2020)

34 Population genomics of the Viking world
Margaryan A.; Lawson D.J.; Sikora M.; Racimo F.; Rasmussen S.; Moltke I.; Cassidy L.M.; Jørsboe E.; Ingason A.; Pedersen M.W.; Korneliussen T.; Wilhelmson H.; Buś M.M.; de Barros Damgaard P.; Martiniano R.; Renaud G.; Bhérer C.; Moreno-Mayar J.V.; Fotakis A.K.; Allen M.; Allmäe R.; Molak M.; Cappellini E.; Scorrano G.; McColl H.; Buzhilova A.; Fox A.; Albrechtsen A.; Schütz B.; Skar B.; Arcini C.; Falys C.; Jonson C.H.; Błaszczyk D.; Pezhemsky D.; Turner-Walker G.; Gestsdóttir H.; Lundstrøm I.; Gustin I.; Mainland I.; Potekhina I.; Muntoni I.M.; Cheng J.; Stenderup J.; Ma J.; Gibson J.; Peets J.; Gustafsson J.; Iversen K.H.; Simpson L.; Strand L.; Loe L.; Sikora M.; Florek M.; Vretemark M.; Redknap M.; Bajka M.; Pushkina T.; Søvsø M.; Grigoreva N.; Christensen T.; Kastholm O.; Uldum O.; Favia P.; Holck P.; Sten S.; Arge S.V.; Ellingvåg S.; Moiseyev V.; Bogdanowicz W.; Magnusson Y.; Orlando L.; Pentz P.; Jessen M.D.; Pedersen A.; Collard M.; Bradley D.G.; Jørkov M.L.; Arneborg J.; Lynnerup N.; Price N.; Gilbert M.T.P.; Allentoft M.E.; Bill J.; Sindbæk S.M.; Hedeager L.; Kristiansen K.; Nielsen R.; Werge T.; Willerslev E.
Nature(2020)

35 Omega-3 fatty acids and risk of cardiovascular disease in Inuit: First prospective cohort study
Senftleber N.K.; Albrechtsen A.; Lauritzen L.; Larsen C.L.; Bjerregaard P.; Diaz L.J.; Rønn P.F.; Jørgensen M.E.
Atherosclerosis(2020)

36 The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders
Andersen M.K.; Jørsboe E.; Skotte L.; Hanghøj K.; Sandholt C.H.; Moltke I.; Grarup N.; Kern T.; Mahendran Y.; Søborg B.; Bjerregaard P.; Larsen C.V.L.; Dahl-Petersen I.K.; Tiwari H.K.; Feenstra B.; Koch A.; Wiener H.W.; Hopkins S.E.; Pedersen O.; Melbye M.; Boyer B.B.; Jørgensen M.E.; Albrechtsen A.^📨; Hansen T.^📨
PLoS Genetics(2020)

37 Estimating narrow-sense heritability using family data from admixed populations
Athanasiadis G.; Speed D.; Andersen M.K.; Appel E.V.R.; Grarup N.; Brandslund I.; Jørgensen M.E.; Larsen C.V.L.; Bjerregaard P.; Hansen T.; Albrechtsen A.
Heredity(2020)

38 Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet
Senftleber N.; Jørgensen M.E.; Jørsboe E.; Imamura F.; Forouhi N.G.; Larsen C.L.; Bjerregaard P.; Hansen T.^📨; Albrechtsen A.^📨
EJHG(2020)

39 A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data
Moreno-Mayar J.V.; Korneliussen T.S.; Dalal J.; Renaud G.; Albrechtsen A.; Nielsen R.; Malaspinas A.-S.
Bioinformatics(2020)

40 DamMet: Ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage
Hanghøj K.; Renaud G.; Albrechtsen A.; Orlando L.
GigaScience(2019)

41 Ancestry-specific association mapping in admixed populations
Skotte L.; Jørsboe E.; Korneliussen T.S.; Moltke I.; Albrechtsen A.
Genetic Epidemiology(2019)

42 Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing
Enroth C.; Poulsen L.D.; Iversen S.; Kirpekar F.; Albrechtsen A.; Vinther J.
NAR(2019)

43 Allele frequency-free inference of close familial relationships from genotypes or low-depth sequencing data
Waples R.K.; Albrechtsen A.; Moltke I.
Mol. Eco.(2019)

44 Genomic diversity and novel genome-wide association with fruit morphology in Capsicum, from 746k polymorphic sites
Colonna V.; D’Agostino N.; Garrison E.; Albrechtsen A.; Meisner J.; Facchiano A.; Cardi T.; Tripodi P.
Sci Rep.(2019)

45 Testing for Hardy–Weinberg equilibrium in structured populations using genotype or low-depth next generation sequencing data
Meisner J.; Albrechtsen A.
Mol. Eco. res(2019)

46 Powerful inference with the D-statistic on low-coverage whole-genome data
Soraggi S.; Wiuf C.; Albrechtsen A.
G3(2018)

47 Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Moreno-Mayar J.V.; Potter B.A.; Vinner L.; Steinrücken M.; Rasmussen S.; Terhorst J.; Kamm J.A.; Albrechtsen A.; Malaspinas A.-S.; Sikora M.; Reuther J.D.; Irish J.D.; Malhi R.S.; Orlando L.; Song Y.S.; Nielsen R.; Meltzer D.J.; Willerslev E.
Nature(2018)

48 Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population
Grarup N.; Moltke I.; Andersen M.K.; Bjerregaard P.; Larsen C.V.L.; Dahl-Petersen I.K.; Jørsboe E.; Tiwari H.K.; Hopkins S.E.; Wiener H.W.; Boyer B.B.; Linneberg A.; Pedersen O.; Jørgensen M.E.; Albrechtsen A.; Hansen T.
Diabetologia(2018)

49 Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup N.; Moltke I.; Andersen M.K.; Dalby M.; Vitting-Seerup K.; Kern T.; Mahendran Y.; Jørsboe E.; Larsen C.V.L.; Dahl-Petersen I.K.; Gilly A.; Suveges D.; Dedoussis G.; Zeggini E.; Pedersen O.; Andersson R.; Bjerregaard P.; Jørgensen M.E.; Albrechtsen A.^📨; Hansen T.^📨
Nature Genetics(2018)

50 Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History
Liu S.; Huang S.; Chen F.; Zhao L.; Yuan Y.; Francis S.S.; Fang L.; Li Z.; Lin L.; Liu R.; Zhang Y.; Xu H.; Li S.; Zhou Y.; Davies R.W.; Liu Q.; Walters R.G.; Lin K.; Ju J.; Korneliussen T.; Yang M.A.; Fu Q.; Wang J.; Zhou L.; Krogh A.; Zhang H.; Wang W.; Chen Z.; Cai Z.; Yin Y.; Yang H.; Mao M.; Shendure J.; Wang J.^📨; Albrechtsen A.^📨; Jin X.^📨; Nielsen R.^📨; Xu X.^📨
Cell(2018)

51 Inferring population structure and admixture proportions in low-depth NGS data
Meisner J.; Albrechtsen A.
Genetics(2018)

52 Ancient genomes revisit the ancestry of domestic and Przewalski’s horses
Gaunitz C.; Fages A.; Hanghøj K.; Albrechtsen A.; Khan N.; Schubert M.; Seguin-Orlando A.; Owens I.J.; Felkel S.; Bignon-Lau O.; Damgaard P.D.B.; Mittnik A.; Mohaseb A.F.; Davoudi H.; Alquraishi S.; Alfarhan A.H.; Al-Rasheid K.A.S.; Crubézy E.; Benecke N.; Olsen S.; Brown D.; Anthony D.; Massy K.; Pitulko V.; Kasparov A.; Brem G.; Hofreiter M.; Mukhtarova G.; Baimukhanov N.; Lõugas L.; Onar V.; Stockhammer P.W.; Krause J.; Boldgiv B.; Undrakhbold S.; Erdenebaatar D.; Lepetz S.; Mashkour M.; Ludwig A.; Wallner B.; Merz V.; Merz I.; Zaibert V.; Willerslev E.; Librado P.; Outram A.K.; Orlando L.
Science(2018)

53 A southern African origin and cryptic structure in the highly mobile plains zebra
Pedersen C.-E.T.; Albrechtsen A.; Etter P.D.; Johnson E.A.; Orlando L.; Chikhi L.; Siegismund H.R.; Heller R.
Nature E&E(2018)

54 Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel E.V.R.; Moltke I.; Jørgensen M.E.; Bjerregaard P.; Linneberg A.; Pedersen O.; Albrechtsen A.; Hansen T.; Grarup N.
EJHG(2018)

55 Genetic architecture of obesity and related metabolic traits — recent insights from isolated populations
Andersen M.K.; Grarup N.; Moltke I.; Albrechtsen A.; Hansen T.
Curr Opin Genetics Dev(2018)

56 Archaic adaptive introgression in TBX15/WARS2
Racimo F.; Gokhman D.; Fumagalli M.; Ko A.; Hansen T.; Moltke I.; Albrechtsen A.; Carmel L.; Huerta-Sanchez E.; Nielsen R.
Mol Biol Evol(2017)

57 Founder Effect of the RETC611Y Mutation in Multiple Endocrine Neoplasia 2A in Denmark: A Nationwide Study
Mathiesen J.S.; Kroustrup J.P.; Vestergaard P.; Stochholm K.; Poulsen P.L.; Rasmussen A.K.; Feldt-Rasmussen U.; Gaustadnes M.; Ørntoft T.F.; Rossing M.; Nielsen F.C.; Albrechtsen A.; Brixen K.; Godballe C.; Frederiksen A.L.
Thyroid(2017)

58 FastNGSadmix: Admixture proportions and principal component analysis of a single NGS sample
Jørsboe E.; Hanghøj K.; Albrechtsen A.
Bioinformatics(2017)

59 Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers
Sikora M.; Seguin-Orlando A.; Sousa V.C.; Albrechtsen A.; Korneliussen T.; Ko A.; Rasmussen S.; Dupanloup I.; Nigst P.R.; Bosch M.D.; Renaud G.; Allentoft M.E.; Margaryan A.; Vasilyev S.V.; Veselovskaya E.V.; Borutskaya S.B.; Deviese T.; Comeskey D.; Higham T.; Manica A.; Foley R.; Meltzer D.J.; Nielsen R.; Excoffier L.; Lahr M.M.; Orlando L.; Willerslev E.
Science(2017)

60 Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation
Rossing M.; Albrechtsen A.; Skytte A.-B.; Jensen U.B.; Ousager L.B.; Gerdes A.-M.; Nielsen F.C.; Hansen T.V.
J Hum genet(2017)

61 Ancient genomic changes associated with domestication of the horse
Librado P.; Gamba C.; Gaunitz C.; Der Sarkissian C.; Pruvost M.; Albrechtsen A.; Fages A.; Khan N.; Schubert M.; Jagannathan V.; Serres-Armero A.; Kuderna L.F.K.; Povolotskaya I.S.; Seguin-Orlando A.; Lepetz S.; Neuditschko M.; Thèves C.; Alquraishi S.; Alfarhan A.H.; Al-Rasheid K.; Rieder S.; Samashev Z.; Francfort H.-P.; Benecke N.; Hofreiter M.; Ludwig A.; Keyser C.; Marques-Bonet T.; Ludes B.; Crubézy E.; Leeb T.; Willerslev E.; Orlando L.
Science(2017)

62 The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: Insights from the Greenlandic Inuit
Pedersen C.-E.T.; Lohmueller K.E.; Grarup N.; Bjerregaard P.; Hansen T.; Siegismund H.R.; Moltke I.; Albrechtsen A.
Genetics(2017)

63 Weighting sequence variants based on their annotation increases power of whole-genome association studies
Sveinbjornsson G.; Albrechtsen A.; Zink F.; Gudjonsson S.A.; Oddson A.; Másson G.; Holm H.; Kong A.; Thorsteinsdottir U.; Sulem P.; Gudbjartsson D.F.; Stefansson K.
Nature Genetics(2016)

64 Estimating IBD tracts from low coverage NGS data
Vieira F.G.; Albrechtsen A.; Nielsen R.
Bioinformatics(2016)

65 Genetics of Type 2 Diabetes: the Power of Isolated Populations
Andersen M.K.; Pedersen C.-E.T.; Moltke I.; Hansen T.; Albrechtsen A.; Grarup N.
Current Diabetes Reports(2016)

66 Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders
Andersen M.K.; Jørsboe E.; Sandholt C.H.; Grarup N.; Jørgensen M.E.; Færgeman N.J.; Bjerregaard P.; Pedersen O.; Moltke I.; Hansen T.; Albrechtsen A.
PLoS Genetics(2016)

67 Next-generation biology: Sequencing and data analysis approaches for non-model organisms
da Fonseca R.R.; Albrechtsen A.; Themudo G.E.; Ramos-Madrigal J.; Sibbesen J.A.; Maretty L.; Zepeda-Mendoza M.L.; Campos P.F.; Heller R.; Pereira R.J.
Mar Genomics(2016)

68 A genomic history of Aboriginal Australia
Malaspinas A.-S.; Westaway M.C.; Muller C.; Sousa V.C.; Lao O.; Alves I.; Bergström A.; Athanasiadis G.; Cheng J.Y.; Crawford J.E.; Heupink T.H.; MacHoldt E.; Peischl S.; Rasmussen S.; Schiffels S.; Subramanian S.; Wright J.L.; Albrechtsen A.; Barbieri C.; Dupanloup I.; Eriksson A.; Margaryan A.; Moltke I.; Pugach I.; Korneliussen T.S.; Levkivskyi I.P.; Moreno-Mayar J.V.; Ni S.; Racimo F.; Sikora M.; Xue Y.; Aghakhanian F.A.; Brucato N.; Brunak Sø.; Campos P.F.; Clark W.; Ellingvåg S.; Fourmile G.; Gerbault P.; Injie D.; Koki G.; Leavesley M.; Logan B.; Lynch A.; Matisoo-Smith E.A.; McAllister P.J.; Mentzer A.J.; Metspalu M.; Migliano A.B.; Murgha L.; Phipps M.E.; Pomat W.; Reynolds D.; Ricaut F.-X.; Siba P.; Thomas M.G.; Wales T.; Wall C.M.; Oppenheimer S.J.; Tyler-Smith C.; Durbin R.; Dortch J.; Manica A.; Schierup M.H.; Foley R.A.; Lahr M.M.; Bowern C.; Wall J.D.; Mailund T.; Stoneking M.; Nielsen R.; Sandhu M.S.; Excoffier L.; Lambert D.M.; Willerslev E.
Nature(2016)

69 Diabetes in population isolates: Lessons from Greenland
Grarup N.; Moltke I.; Albrechtsen A.; Hansen T.
Review of Diabetic Studies(2015)

70 Evolutionary genomics and conservation of the endangered Przewalski’s horse
Der Sarkissian C.; Ermini L.; Schubert M.; Yang M.A.; Librado P.; Fumagalli M.; Jónsson H.; Bar-Gal G.K.; Albrechtsen A.; Vieira F.G.; Petersen B.; Ginolhac A.; Seguin-Orlando A.; Magnussen K.; Fages A.; Gamba C.; Lorente-Galdos B.; Polani S.; Steiner C.; Neuditschko M.; Jagannathan V.; Feh C.; Greenblatt C.L.; Ludwig A.; Abramson N.I.; Zimmermann W.; Schafberg R.; Tikhonov A.; Sicheritz-Ponten T.; Willerslev E.; Marques-Bonet T.; Ryder O.A.; McCue M.; Rieder S.; Leeb T.; Slatkin M.; Orlando L.
Current Biology(2015)

71 Partial USH2A deletions contribute to Usher syndrome in Denmark
Dad S.; Rendtorff N.D.; Kann E.; Albrechtsen A.; Mehrjouy M.M.; Bak M.; Tommerup N.; Tranebjærg L.; Rosenberg T.; Jensen H.; Møller L.B.
EJHG(2015)

72 Uncovering the genetic history of the present-day greenlandic population
Moltke I.; Fumagalli M.; Korneliussen T.S.; Crawford J.E.; Bjerregaard P.; Jørgensen M.E.; Grarup N.; Gulløv H.C.; Linneberg A.; Pedersen O.; Hansen T.^📨; Nielsen R.^📨; Albrechtsen A.^📨
AJHG(2015)

73 Tracking the origins of Yakutian horses and the genetic basis for their fast adaptation to subarctic environments
Librado P.; Der Sarkissian C.; Ermini L.; Schubert M.; Jónsson H.; Albrechtsen A.; Fumagalli M.; Yang M.A.; Gamba C.; Seguin-Orlando A.; Mortensen C.D.; Petersen B.; Hoove C.A.; Lorente-Galdos B.; Nedoluzhko A.; Boulygina E.; Tsygankova S.; Neuditschko M.; Jagannathan V.; Thèves C.; Alfarhan A.H.; Alquraishi S.A.; Al-Rasheid K.A.S.; Sicheritz-Ponten T.; Popov R.; Grigoriev S.; Alekseev A.N.; Rubin E.M.; McCue M.; Rieder S.; Leeb T.; Tikhonov A.; Crubézy E.; Slatkin M.; Marques-Bonet T.; Nielsen R.; Willerslev E.; Kantanen J.; Prokhortchouk E.; Orlando L.
PNAS(2015)

74 The ancestry and affiliations of Kennewick Man
Rasmussen M.; Sikora M.; Albrechtsen A.; Korneliussen T.S.; Moreno-Mayar J.V.; Poznik G.D.; Zollikofer C.P.E.; Ponce De León M.S.; Allentoft M.E.; Moltke I.; Jónsson H.; Valdiosera C.; Malhi R.S.; Orlando L.; Bustamante C.D.; Stafford T.W., Jr.; Meltzer D.J.; Nielsen R.; Willerslev E.
Nature(2015)

75 The origin and evolution of maize in the Southwestern United States
Da Fonseca R.R.; Smith B.D.; Wales N.; Cappellini E.; Skoglund P.; Fumagalli M.; Samaniego J.A.; Carøe C.; Ávila-Arcos M.C.; Hufnagel D.E.; Korneliussen T.S.; Vieira F.G.; Jakobsson M.; Arriaza B.; Willerslev E.; Nielsen R.; Hufford M.B.; Albrechtsen A.; Ross-Ibarra J.; Gilbert M.T.P.
Nature Plants(2015)

76 Greenlandic Inuit show genetic signatures of diet and climate adaptation
Fumagalli M.; Moltke I.; Grarup N.; Racimo F.; Bjerregaard P.; Jørgensen M.E.; Korneliussen T.S.; Gerbault P.; Skotte L.; Linneberg A.; Christensen C.; Brandslund I.; Jørgensen T.; Huerta-Sánchez E.; Schmidt E.B.; Pedersen O.; Hansen T.^📨; Albrechtsen A.^📨; Nielsen R.^📨
Science(2015)

77 Genomic evidence for the Pleistocene and recent population history of Native Americans
Raghavan M.; Steinrücken M.; Harris K.; Schiffels S.; Rasmussen S.; DeGiorgio M.; Albrechtsen A.; Valdiosera C.; Ávila-Arcos M.C.; Malaspinas A.-S.; … Manica A.; Durbin R.; Bustamante C.D.; Song Y.S.; Nielsen R.; Willerslev E.
Science(2015)

78 Genomic structure in Europeans dating back at least 36,200 years
Seguin-Orlando A.; Korneliussen T.S.; Sikora M.; Malaspinas A.-S.; Manica A.; Moltke I.; Albrechtsen A.; Ko A.; Margaryan A.; Moiseyev V.; Goebel T.; Westaway M.; Lambert D.; Khartanovich V.; Wall J.D.; Nigst P.R.; Foley R.A.; Lahr M.M.; Nielsen R.; Orlando L.; Willerslev E.
Science(2014)

79 The genetic prehistory of the New World Arctic
Raghavan M.; DeGiorgio M.; Albrechtsen A.; Moltke I.; Skoglund P.; Korneliussen T.S.; Grønnow B.; Appelt M.; Gulløv H.C.; Friesen T.M.; Fitzhugh W.; Malmström H.; Rasmussen S.; Olsen J.; Melchior L.; Fuller B.T.; Fahrni S.M.; Stafford T., Jr.; Grimes V.; Renouf M.A.P.; Cybulski J.; Lynnerup N.; Lahr M.M.; Britton K.; Knecht R.; Arneborg J.; Metspalu M.; Cornejo O.E.; Malaspinas A.-S.; Wang Y.; Rasmussen M.; Raghavan V.; Hansen T.V.O.; Khusnutdinova E.; Pierre T.; Dneprovsky K.; Andreasen C.; Lange H.; Hayes M.G.; Coltrain J.; Spitsyn V.A.; Götherström A.; Orlando L.; Kivisild T.; Villems R.; Crawford M.H.; Nielsen F.C.; Dissing J.; Heinemeier J.; Meldgaard M.; Bustamante C.; O’Rourke D.H.; Jakobsson M.; Gilbert M.T.P.; Nielsen R.; Willerslev E.
Science(2014)

80 Speciation with gene flow in equids despite extensive chromosomal plasticity
Jónsson H.; Schubert M.; Seguin-Orlando A.; Ginolhac A.; Petersen L.; Fumagalli M.; Albrechtsen A.; Petersen B.; Korneliussen T.S.; Vilstrup J.T.; Lear T.; Myka J.L.; Lundquist J.; Miller D.C.; Alfarhan A.H.; Alquraishi S.A.; Al-Rasheid K.A.S.; Stagegaard J.; Strauss G.; Bertelsen M.F.; Sicheritz-Ponten T.; Antczak D.F.; Bailey E.; Nielsen R.; Willerslev E.; Orlando L.
PNAS(2014)

81 ANGSD: Analysis of Next Generation Sequencing Data
Korneliussen T.S.; Albrechtsen A.; Nielsen R.
BMC Bioinformatics(2014)

82 RelateAdmix: A software tool for estimating relatedness between admixed individuals
Moltke I.; Albrechtsen A.
Bioinformatics(2014)

83 Upper palaeolithic Siberian genome reveals dual ancestry of native Americans
Raghavan M.; Skoglund P.; Graf K.E.; Metspalu M.; Albrechtsen A.; Moltke I.; Rasmussen S.; Stafford T.W., Jr.; Orlando L.; Metspalu E.; Karmin M.; Tambets K.; Rootsi S.; Mägi R.; Campos P.F.; Balanovska E.; Balanovsky O.; Khusnutdinova E.; Litvinov S.; Osipova L.P.; Fedorova S.A.; Voevoda M.I.; Degiorgio M.; Sicheritz-Ponten T.; Brunak Sø.; Demeshchenko S.; Kivisild T.; Villems R.; Nielsen R.; Jakobsson M.; Willerslev E.
Nature(2014)

84 Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil
Malaspinas A.-S.; Lao O.; Schroeder H.; Rasmussen M.; Raghavan M.; Moltke I.; Campos P.F.; Sagredo F.S.; Rasmussen S.; Gonçalves V.F.; Albrechtsen A.; Allentoft M.E.; Johnson P.L.F.; Li M.; Reis S.; Bernardo D.V.; Degiorgio M.; Duggan A.T.; Bastos M.; Wang Y.; Stenderup J.; Moreno-Mayar J.V.; Brunak Sø.; Sicheritz-Ponten T.; Hodges E.; Hannon G.J.; Orlando L.; Price T.D.; Jensen J.D.; Nielsen R.; Heinemeier J.; Olsen J.; Rodrigues-Carvalho C.; Lahr M.M.; Neves W.A.; Kayser M.; Higham T.; Stoneking M.; Pena S.D.J.; Willerslev E.
Current Biology(2014)

85 Prehistoric genomes reveal the genetic foundation and cost of horse domestication
Schubert M.; Jónsson H.; Chang D.; Der Sarkissian C.; Ermini L.; Ginolhac A.; Albrechtsen A. … Nielsen R.; Excoffier L.; Willerslev E.; Shapiro B.; Orlando L.
PNAS(2014)

86 Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis
Laursen J.H.; Søndergaard H.B.; Albrechtsen A.; Frikke-Schmidt R.; Koch-Henriksen N.; Soelberg Sørensen P.; Sellebjerg F.; Oturai A.
Multiple Sclerosis(2014)

87 Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population
Li S.; Besenbacher S.; Li Y.; Kristiansen K.; Grarup N.; Albrechtsen A.; Sparsø T.; Korneliussen T.; Hansen T.; Wang J.; Nielsen R.; Pedersen O.; Bolund L.; Schierup M.H.
EJHG(2014)

88 The genome of a Late Pleistocene human from a Clovis burial site in western Montana
Rasmussen M.; Anzick S.L.; Waters M.R.; Skoglund P.; Degiorgio M.; Stafford Jr. T.W.; Rasmussen S.; Moltke I.; Albrechtsen A.; Doyle S.M.; Poznik G.D.; Gudmundsdottir V.; Yadav R.; Malaspinas A.-S.; Samuel Stockton White V.; Allentoft M.E.; Cornejo O.E.; Tambets K.; Eriksson A.; Heintzman P.D.; Karmin M.; Korneliussen T.S.; Meltzer D.J.; Pierre T.L.; Stenderup J.; Saag L.; Warmuth V.M.; Lopes M.C.; Malhi R.S.; Brunak Sø.; Sicheritz-Ponten T.; Barnes I.; Collins M.; Orlando L.; Balloux F.; Manica A.; Gupta R.; Metspalu M.; Bustamante C.D.; Jakobsson M.; Nielsen R.; Willerslev E.
Nature(2014)

89 A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Moltke I.; Grarup N.; Jørgensen M.E.; Bjerregaard P.; Treebak J.T.; Fumagalli M.; Korneliussen T.S.; Andersen M.A.; Nielsen T.S.; Krarup N.T.; Gjesing A.P.; Zierath J.R.; Linneberg A.; Wu X.; Sun G.; Jin X.; Al-Aama J.; Wang J.; Borch-Johnsen K.; Pedersen O.; Nielsen R.^📨; Albrechtsen A.^📨; Hansen T.^📨
Nature(2014)

90 Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort
Larsen M.H.; Albrechtsen A.; Thørner L.W.; Werge T.; Hansen T.; Gether U.; Haastrup E.; Ullum H.
PLoS ONE(2013)

91 Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen A.; Grarup N.; Li Y.; Sparsø T.; Tian G.; Cao H.; Jiang T.; Kim S.Y.; Korneliussen T.; Li Q.; Nie C.; Wu R.; Skotte L.; Morris A.P.; Ladenvall C.; Cauchi S.; Stančáková A.; Andersen G.; Astrup A.; Banasik K.; Bennett A.J.; Bolund L.; Charpentier G.; Chen Y.; Dekker J.M.; Doney A.S.F.; Dorkhan M.; Forsen T.; Frayling T.M.; Groves C.J.; Gui Y.; Hallmans G.; Hattersley A.T.; He K.; Hitman G.A.; Holmkvist J.; Huang S.; Jiang H.; Jin X.; Justesen J.M.; Kristiansen K.; Kuusisto J.; Lajer M.; Lantieri O.; Li W.; Liang H.; Liao Q.; Liu X.; Ma T.; Ma X.; Manijak M.P.; Marre M.; Mokrosiński J.; Morris A.D.; Mu B.; Nielsen A.A.; Nijpels G.; Nilsson P.; Palmer C.N.A.; Rayner N.W.; Renström F.; Ribel-Madsen R.; Robertson N.; Rolandsson O.; Rossing P.; Schwartz T.W.; Slagboom P.E.; Sterner M.; Tang M.; Tarnow L.; Tuomi T.; Van’T Riet E.; Van Leeuwen N.; Varga T.V.; Vestmar M.A.; Walker M.; Wang B.; Wang Y.; Wu H.; Xi F.; Yengo L.; Yu C.; Zhang X.; Zhang J.; Zhang Q.; Zhang W.; Zheng H.; Zhou Y.; Altshuler D.; ‘T Hart L.M.; Franks P.W.; Balkau B.; Froguel P.; McCarthy M.I.; Laakso M.; Groop L.; Christensen C.; Brandslund I.; Lauritzen T.; Witte D.R.; Linneberg A.; Jørgensen T.; Hansen T.; Wang J.; Nielsen R.; Pedersen O.
Diabetologia(2013)

92 Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation
Vieira F.G.; Fumagalli M.; Albrechtsen A.; Nielsen R.
Genome Research(2013)

93 Recalibrating equus evolution using the genome sequence of an early Middle Pleistocene horse
Orlando L.; Ginolhac A.; Zhang G.; Froese D.; Albrechtsen A.; Stiller M.; Schubert M.; Cappellini E.; Petersen B.; Moltke I.; Johnson P.L.F.; Fumagalli M.; Vilstrup J.T.; Raghavan M.; Korneliussen T.; Malaspinas A.-S.; Vogt J.; Szklarczyk D.; Kelstrup C.D.; Vinther J.; Dolocan A.; Stenderup J.; Velazquez A.M.V.; Cahill J.; Rasmussen M.; Wang X.; Min J.; Zazula G.D.; Seguin-Orlando A.; Mortensen C.; Magnussen K.; Thompson J.F.; Weinstock J.; Gregersen K.; Røed K.H.; Eisenmann V.; Rubin C.J.; Miller D.C.; Antczak D.F.; Bertelsen M.F.; Brunak Sø.; Al-Rasheid K.A.S.; Ryder O.; Andersson L.; Mundy J.; Krogh A.; Gilbert M.T.P.; Kjær K.; Sicheritz-Ponten T.; Jensen L.J.; Olsen J.V.; Hofreiter M.; Nielsen R.; Shapiro B.; Wang J.; Willerslev E.
Nature(2013)

94 Calculation of Tajima’s D and other neutrality test statistics from low depth next-generation sequencing data
Korneliussen T.S.; Moltke I.; Albrechtsen A.; Nielsen R.
BMC Bioinformatics(2013)

95 Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes
Lohmueller K.E.; Sparsø T.; Li Q.; Andersson E.; Korneliussen T.; Albrechtsen A.; Banasik K.; Grarup N.; Hallgrimsdottir I.; Kiil K.; Kilpeläinen T.O.; Krarup N.T.; Pers T.H.; Sanchez G.; Hu Y.; Degiorgio M.; Jørgensen T.; Sandbæk A.; Lauritzen T.; Brunak Sø.; Kristiansen K.; Li Y.; Hansen T.; Wang J.; Nielsen R.; Pedersen O.
AJHG(2013)

96 Genetic Architecture of Vitamin B12 and Folate Levels Uncovered Applying Deeply Sequenced Large Datasets
Grarup N.; Sulem P.; Sandholt C.H.; Thorleifsson G.; Ahluwalia T.S.; Steinthorsdottir V.; Bjarnason H.; Gudbjartsson D.F.; Magnusson O.T.; Sparsø T.; Albrechtsen A.; Kong A.; Masson G.; Tian G.; Cao H.; Nie C.; Kristiansen K.; Husemoen L.L.; Thuesen B.; Li Y.; Nielsen R.; Linneberg A.; Olafsson I.; Eyjolfsson G.I.; Jørgensen T.; Wang J.; Hansen T.; Thorsteinsdottir U.; Stefánsson K.; Pedersen O.
PLoS Genetics(2013)

97 Quantifying population genetic differentiation from next-generation sequencing data
Fumagalli M.; Vieira F.G.; Korneliussen T.S.; Linderoth T.; Huerta-Sánchez E.; Albrechtsen A.; Nielsen R.
Genetics(2013)

98 Estimating individual admixture proportions from next generation sequencing data
Skotte L.; Korneliussen T.S.; Albrechtsen A.
Genetics(2013)

99 SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data
Nielsen R.; Korneliussen T.; Albrechtsen A.; Li Y.; Wang J.
PLoS ONE(2012)

100 Association Testing for Next-Generation Sequencing Data Using Score Statistics
Skotte L.; Korneliussen T.S.; Albrechtsen A.
Genetic Epidemiology(2012)

101 Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome
Lohmueller K.E.; Albrechtsen A.; Li Y.; Kim S.Y.; Korneliussen T.; Vinckenbosch N.; Tian G.; Huerta-Sanchez E.; Feder A.F.; Grarup N.; Jørgensen T.; Jiang T.; Witte D.R.; Sandbæk A.; Hellmann I.; Lauritzen T.; Hansen T.; Pedersen O.; Wang J.; Nielsen R.
PLoS Genetics(2011)

102 A method for detecting IBD regions simultaneously in multiple individuals - With applications to disease genetics
Moltke I.; Albrechtsen A.; Hansen T.V.O.; Nielsen F.C.; Nielsen R.
Genome Research(2011)

103 An aboriginal Australian genome reveals separate human dispersals into Asia
Rasmussen M.; Guo X.; Wang Y.; Lohmueller K.E.; Rasmussen S.; Albrechtsen A.; Skotte L.; Lindgreen S.; Metspalu M.; Jombart T.; Kivisild T.; Zhai W.; Eriksson A.; Manica A.; Orlando L.; De La Vega F.M.; Tridico S.; Metspalu E.; Nielsen K.; Ávila-Arcos M.C.; Víctor Moreno-Mayar J.; Muller C.; Dortch J.; Gilbert M.T.P.; Lund O.; Wesolowska A.; Karmin M.; Weinert L.A.; Wang B.; Li J.; Tai S.; Xiao F.; Hanihara T.; Van Driem G.; Jha A.R.; Ricaut F.-X.; De Knijff P.; Migliano A.B.; Romero I.G.; Kristiansen K.; Lambert D.M.; Brunak S.; Forster P.; Brinkmann B.; Nehlich O.; Bunce M.; Richards M.; Gupta R.; Bustamante C.D.; Krogh A.; Foley R.A.; Lahr M.M.; Balloux F.; Sicheritz-Pontén T.; Villems R.; Nielsen R.; Wang J.; Willerslev E.
Science(2011)

104 Estimation of allele frequency and association mapping using next-generation sequencing data
Kim S.Y.; Lohmueller K.E.; Albrechtsen A.; Li Y.; Korneliussen T.; Tian G.; Grarup N.; Jiang T.; Andersen G.; Witte D.; Jorgensen T.; Hansen T.; Pedersen O.; Wang J.; Nielsen R.
BMC Bioinformatics(2011)

105 Genotype and SNP calling from next-generation sequencing data
Nielsen R.; Paul J.S.; Albrechtsen A.; Song Y.S.
Nature Reviews Genetics(2011)

106 Ancient human genome sequence of an extinct Palaeo-Eskimo
Rasmussen M.; Li Y.; Lindgreen S.; Pedersen J.S.; Albrechtsen A.; Moltke I.; Metspalu M.; Metspalu E.; Kivisild T.; Gupta R.; Bertalan M.; Nielsen K.; Gilbert M.T.P.; Wang Y.; Raghavan M.; Campos P.F.; Kamp H.M.; Wilson A.S.; Gledhill A.; Tridico S.; Bunce M.; Lorenzen E.D.; Binladen J.; Guo X.; Zhao J.; Zhang X.; Zhang H.; Li Z.; Chen M.; Orlando L.; Kristiansen K.; Bak M.; Tommerup N.; Bendixen C.; Pierre T.L.; Gronnow B.; Meldgaard M.; Andreasen C.; Fedorova S.A.; Osipova L.P.; Higham T.F.G.; Ramsey C.B.; Hansen T.V.O.; Nielsen F.C.; Crawford M.H.; Brunak S.; Sicheritz-Pont́n T.; Villems R.; Nielsen R.; Krogh A.; Wang J.; Willerslev E.
Nature(2010)

107 Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Gjesing A.P.; Larsen L.H.; Torekov S.S.; Hainerová I.A.; Kapur R.; Johansen A.; Albrechtsen A.; Boj S.; Holst B.; Harper A.; Urhammer S.A.; Borch-Johnsen K.; Pisinger C.; Echwald S.M.; Eiberg H.; Astrup A.; Lebl J.; Ferrer J.; Schwartz T.W.; Hansen T.; Pedersen O.
PLoS ONE(2010)

108 Ascertainment biases in SNP chips affect measures of population divergence
Albrechtsen A.; Nielsen F.C.; Nielsen R.
Mol Biol Evol(2010)

109 Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: Implications for genetic screening of Greenlandic Inuit families with high risk for breast and/or ovarian cancer
Hansen T.V.O.; Jønson L.; Albrechtsen A.; Steffensen A.Y.; Bergsten E.; Myrhøj T.; Ejlertsen B.; Nielsen F.C.
Breast Cancer Res Treat(2010)

110 Natural selection and the distribution of identity-by-descent in the human genome
Albrechtsen A.; Moltke I.; Nielsen R.
Genetics(2010)

111 Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes
Fosgerau K.; Galle P.; Hansen T.; Albrechtsen A.; De Lemos Rieper C.; Pedersen B.K.; Larsen L.K.; Thomsen A.R.; Pedersen O.; Hansen M.B.; Steensberg A.
Journal of Endocrinology(2010)

112 Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
Li Y.; Vinckenbosch N.; Tian G.; Huerta-Sanchez E.; Jiang T.; Jiang H.; Albrechtsen A.; Andersen G.; Cao H.; Korneliussen T.; Grarup N.; Guo Y.; Hellman I.; Jin X.; Li Q.; Liu J.; Liu X.; Sparsø T.; Tang M.; Wu H.; Wu R.; Yu C.; Zheng H.; Astrup A.; Bolund L.; Holmkvist J.; Jørgensen T.; Kristiansen K.; Schmitz O.; Schwartz T.W.; Zhang X.; Li R.; Yang H.; Wang J.; Hansen T.; Pedersen O.; Nielsen R.; Wang J.
Nature Genetics(2010)

113 Segregation distortion in chicken and the evolutionary consequences of female meiotic drive in birds
Axelsson E.; Albrechtsen A.; Van A.P.; Li L.; Megens H.J.; Vereijken A.L.J.; Crooijmans R.P.M.A.; Groenen M.A.M.; Ellegren H.; Willerslev E.; Nielsen R.
Heredity(2010)

114 Identification of a novel locus for a USH3 like syndrome combined with congenital cataract
Dad S.; Østergaard E.; Thykjær T.; Albrectsen A.; Ravn K.; Rosenberg T.; Møller L.B.
Clinical Genetics(2010)

115 Combined analyses of 20 common obesity susceptibility variants
Sandholt C.H.; Sparsø T.; Grarup N.; Albrechtsen A.; Almind K.; Hansen L.; Toft U.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetes(2010)

116 Darwinian and demographic forces affecting human protein coding genes
Nielsen R.; Hubisz M.J.; Hellmann I.; Torgerson D.; Andrés A.M.; Albrechtsen A.; Gutenkunst R.; Adams M.D.; Cargill M.; Boyko A.; Indap A.; Bustamante C.D.; Clark A.G.
Genome Research(2009)

117 Functional SOCS1 polymorphisms are associated with variation in obesity in whites
Gylvin T.; Ek J.; Nolsøe R.; Albrechtsen A.; Andersen G.; Bergholdt R.; Brorsson C.; Bang-Berthelsen C.H.; Hansen T.; Karlsen A.E.; Billestrup N.; Borch-Johnsen K.; Jørgensen T.; Pedersen O.; Mandrup-Poulsen T.; Nerup J.; Pociot F.
Diabetes Obes Metab(2009)

118 The validation and assessment of machine learning: A game of prediction from high-dimensional data
Pers T.H.; Albrechtsen A.; Holst C.; Sørensen T.I.A.; Gerds T.A.
PLoS ONE(2009)

119 Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction
Sparsø T.; Grarup N.; Andreasen C.; Albrechtsen A.; Holmkvist J.; Andersen G.; Jørgensen T.; Borch-Johnsen K.; Sandbæk A.; Lauritzen T.; Madsbad S.; Hansen T.; Pedersen O.
Diabetologia(2009)

120 A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads
Rose C.S.; Grarup N.; Krarup N.T.; Poulsen P.; Wegner L.; Nielsen T.; Banasik K.; Færch K.; Andersen G.; Albrechtsen A.; Borch-Johnsen K.; Clausen J.O.; Jørgensen T.; Vaag A.; Pedersen O.; Hansen T.
Diabetologia(2009)

121 Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families
Hansen T.V.O.; Jønson L.; Albrechtsen A.; Andersen M.K.; Ejlertsen B.; Nielsen F.C.
Breast Cancer Res Treat(2009)

122 Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium
Albrechtsen A.; Korneliussen T.S.; Moltke I.; van Overseem Hansen T.; Nielsen F.C.; Nielsen R.
Genetic Epidemiology(2009)

123 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
Rung J.; Cauchi S.; Albrechtsen A.*; Shen L.; Rocheleau G.; Cavalcanti-Proença C.; Bacot F.; Balkau B.; Belisle A.; Borch-Johnsen K.; Charpentier G.; Dina C.; Durand E.; Elliott P.; Hadjadj S.; Järvelin M.-R.; Laitinen J.; Lauritzen T.; Marre M.; Mazur A.; Meyre D.; Montpetit A.; Pisinger C.; Posner B.; Poulsen P.; Pouta A.; Prentki M.; Ribel-Madsen R.; Ruokonen A.; Sandbaek A.; Serre D.; Tichet J.; Vaxillaire M.; Wojtaszewski J.F.P.; Vaag A.; Hansen T.; Polychronakos C.; Pedersen O.; Froguel P.; Sladek R.
Nature Genetics(2009)

124 A common Greenlandic Inuit BRCA1 RING domain founder mutation
Hansen T.V.O.; Ejlertsen B.; Albrechtsen A.; Bergsten E.; Bjerregaard P.; Hansen T.; Myrhøj T.; Nielsen P.B.; Timmermans-Wielenga V.; Andersen M.K.; Jønson L.; Nielsen F.C.
Breast Cancer Res Treat(2009)

125 The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects
Grarup N.; Andreasen C.H.; Andersen M.K.; Albrechtsen A.; Sandbæk A.; Lauritzen T.; Borch-Johnsen K.; Jørgensen T.; Schmitz O.; Hansen T.; Pedersen O.
J Clin Endocrinol Metab(2008)

126 The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes
Sparsø T.; Andersen G.; Nielsen T.; Burgdorf K.S.; Gjesing A.P.; Nielsen A.L.; Albrechtsen A.; Rasmussen S.S.; Jørgensen T.; Borch-Johnsen K.; Sandbæk A.; Lauritzen T.; Madsbad S.; Hansen T.; Pedersen O.
Diabetologia(2008)

127 Novel de novo BRCA2 mutation in a patient with a family history of breast cancer
Hansen T.V.O.; Bisgaard M.L.; Jønson L.; Albrechtsen A.; Filtenborg-Barnkob B.; Eiberg H.; Ejlertsen B.; Nielsen F.C.
BMC Medical Genetics(2008)

128 Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
Andreasen C.H.; Stender-Petersen K.L.; Mogensen M.S.; Torekov S.S.; Wegner L.; Andersen G.; Nielsen A.L.; Albrechtsen A.; Borch-Johnsen K.; Rasmussen S.S.; Clausen J.O.; Sandbæk A.; Lauritzen T.; Hansen L.; Jørgensen T.; Pedersen O.; Hansen T.
Diabetes(2008)

129 Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged danes
Grarup N.; Andersen G.; Krarup N.T.; Albrechtsen A.; Schmitz O.; Joørgensen T.; Borch-Johnsen K.; Hansen T.; Pedersen O.
Diabetes(2008)

130 Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
Sparsø T.; Andersen G.; Albrechtsen A.; Jørgensen T.; Borch-Johnsen K.; Sandbæk A.; Lauritzen T.; Wasson J.; Permutt M.A.; Glaser B.; Madsbad S.; Pedersen O.; Hansen T.
Diabetologia(2008)

131 Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Grarup N.; Andersen M.K.; Andreasen C.H.; Albrechtsen A.; Borch-Johnsen K.; Jørgensen T.; Auwerx J.; Schmitz O.; Hansen T.; Pedersen O.
J Clin Endocrinol Metab(2007)

132 A -243A→G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged white subjects
Boesgaard T.W.; Castella S.I.; Andersen G.; Albrechtsen A.; Sparsø T.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetic Medicine(2007)

133 A bayesian multilocus association method: Allowing for higher-order interaction in association studies
Albrechtsen A.; Castella S.; Andersen G.; Hansen T.; Pedersen O.; Nielsen R.
Genetics(2007)

134 Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes
Larsen L.H.; Rose C.S.; Sparsø T.; Overgaard J.; Torekov S.S.; Grarup N.; Jensen D.P.; Albrechtsen A.; Andersen G.; Ek J.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Int J Obes(2007)

135 Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: Validation and extension of genome-wide association studies
Grarup N.; Rose C.S.; Andersson E.A.; Andersen G.; Nielsen A.L.; Albrechtsen A.; Clausen J.O.; Rasmussen S.S.; Jørgensen T.; Sandbæk A.; Lauritzen T.; Schmitz O.; Hansen T.; Pedersen O.
Diabetes(2007)

136 Studies of associations between the Arg389Gly polymorphism of the β1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects
Gjesing A.P.; Andersen G.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetic Medicine(2007)

137 Variation in the peroxisome proliferator-activated receptor δ gene in relation to common metabolic traits in 7,495 middle-aged white people
Grarup N.; Albrechtsen A.; Ek J.; Borch-Johnsen K.; Jørgensen T.; Schmitz O.; Hansen T.; Pedersen O.
Diabetologia(2007)

138 A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4α gene (HNF4A) associates with late-onset diabetes
Ek J.; Hansen S.P.; Lajer M.; Nicot C.; Boesgaard T.W.; Pruhova S.; Johansen A.; Albrechtsen A.; Yderstræde K.; Lauenborg J.; Parrizas M.; Boj S.F.; Jørgensen T.; Borch-Johnsen K.; Damm P.; Ferrer J.; Lebl J.; Pedersen O.; Hansen T.
Diabetes(2006)

139 Large-scale study of the -232C > G polymorphism of PCK1 in Type 2 diabetes
Wegner L.; Andersen G.; Albrechtsen A.; Sparsø T.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetic Medicine(2006)

140 Variants in the 5′ region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects
Torekov S.S.; Larsen L.H.; Andersen G.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetologia(2006)

141 Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects
Grarup N.; Urhammer S.A.; Ek J.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetologia(2006)

142 Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes
Andersen G.; Overgaard J.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetologia(2006)