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1 Introgression and disruption of migration routes have shaped the genetic integrity of wildebeest populations.
Xiaodong Liu* , Long Lin* , Mikkel-Holger S. Sinding* , Laura D. Bertola, Kristian Hanghøj, Liam Quinn, Genís Garcia-Erill, Malthe Sebro Rasmussen, Mikkel Schubert, Patrícia Pečnerová, Renzo F. Balboa, Zilong Li, Michael P. Heaton, Timothy P. L. Smith, Rui Resende Pinto, Xi Wang, Josiah Kuja, Anna Brüniche-Olsen, Jonas Meisner, Cindy G. Santander, Joseph O. Ogutu, Charles Masembe, Rute R. da Fonseca, Vincent Muwanika, Hans R. Siegismund, Anders Albrechtsen^📨, Ida Moltke^📨, Rasmus Heller^📨
Nature Communications 15, 2921 (2024)

2 Giraffe lineages are shaped by major ancient admixture events
Laura D. Bertola* , Liam Quinn* , Kristian Hanghøj* , Genís Garcia-Erill, Malthe Sebro Rasmussen, Renzo F. Balboa, Jonas Meisner, Thomas Bøggild, Xi Wang, Long Lin, Casia Nursyifa, Xiaodong Liu, Zilong Li, Mumbi Chege, Yoshan Moodley, Anna Brüniche-Olsen, Josiah Kuja, Mikkel Schubert, Morris Agaba, Cindy G. Santander, Mikkel-Holger S. Sinding, Vincent Muwanika, Charles Masembe, Hans R. Siegismund, Ida Moltke ^📨 , Anders Albrechtsen ^📨, Rasmus Heller ^📨,
Current Biology,2024

3 African bushpigs exhibit porous species boundaries and appeared in Madagascar concurrently with human arrival
Balboa* , Bertola* , Brüniche-Olsen* , … Moltke ^📨, Albrechtsen ^📨, Heller ^📨;
Nature Communications 15, 172 (2024)

4 Estimating admixture pedigrees of recent hybrids without a contiguous reference genome
Genís Garcia-Erill^📨, Kristian Hanghøj, Rasmus Heller, Carsten Wiuf, Anders Albrechtsen
Mol Ecol Resour 23(7) 2023

5 Evaluation of population structure inferred by principal component analysis or the admixture model.
Jan van Waaij* ^📨, Song Li* , Genís Garcia-Erill* , Anders Albrechtsen, Carsten Wiuf^📨;
Genetics: 2023, 225(2);

6 Fast and accurate out-of-core PCA framework for large scale biobank data.
Zilong Li^📨, Jonas Meisner, Anders Albrechtsen^📨
Genome Res: 2023, 33(9);1599-1608

7 A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland
Anne Cathrine Baun Thuesen* , Frederik Filip Stæger* , …, Anders Albrechtsen^📨, Ida Moltke^📨, Torben Hansen^📨
Lancet Reg Health Eur: 2023, 24;100529

8 An LDLR missense variant poses high risk of familial hypercholesterolemia in 30% of Greenlanders and offers potential of early cardiovascular disease intervention
Emil Jørsboe, Mette K Andersen,…, Ida Moltke^📨, Anders Albrechtsen^📨, Torben Hansen^📨
HGG Adv: 2022, 3(4);100118

9 Haplotype and population structure inference using neural networks in whole-genome sequencing data.
Jonas Meisner^📨, Anders Albrechtsen
Genome Res: 2022, 32(8);1542-52

10 Loss of Sucrase-Isomaltase Function Increases Acetate Levels and Improves Metabolic Health in Greenlandic Cohorts.
Mette K Andersen* , Line Skotte* , Emil Jørsboe* ,…,Ida Moltke^📨, Torben Hansen^📨, Anders Albrechtsen^📨
Gastroenterology: 2022, 162(4);1171-1182.e3

11 Population genomics of the muskox’ resilience in the near absence of genetic variation
Pečnerová P.; Lord E.; Garcia-Erill G.; Hanghøj K.; Rasmussen M.S.; Meisner J.; Liu X.; van der Valk T.; Santander C.G.; Quinn L.; Lin L.; Liu S.; Carøe C.; Dalerum F.; Götherström A.; Måsviken J.; Vartanyan S.; Raundrup K.; Al-Chaer A.; Rasmussen L.; Hvilsom C.; Heide-Jørgensen M.P.; Sinding M.-H.S.; Aastrup P.; Van Coeverden de Groot P.J.; Schmidt N.M.; Albrechtsen A.; Dalén L.; Heller R.; Moltke I.; Siegismund H.R.
Mol. Eco.(2023)

12 Genetic Loss of Sucrase-Isomaltase Function: Mechanisms, Implications, and Future Perspectives
Senftleber N.K.; Ramne S.; Moltke I.; Jørgensen M.E.; Albrechtsen A.; Hansen T.; Andersen M.K.
Appl Clin Genet(2023)

13 Identifying the genetic causes of phenotypically diagnosed Pakistani mucopolysaccharidoses patients by whole genome sequencing
Gul R.; Firasat S.; Schubert M.; Ullah A.; Peña E.; Thuesen A.C.B.; Hussain M.; Staeger F.F.; Gjesing A.P.; Albrechtsen A.; Hansen T.
Front. genet(2023)

14 GWAS of lipids in Greenlanders finds association signals shared with Europeans and reveals an independent PCSK9 association signal
Senftleber N.K.; Andersen M.K.; Jørsboe E.; Stæger F.F.; Nøhr A.K.; Garcia-Erill G.; Meisner J.; Santander C.G.; Balboa R.F.; Gilly A.; Bjerregaard P.; Larsen C.V.L.; Grarup N.; Jørgensen M.E.; Zeggini E.; Moltke I.^📨; Hansen T.^📨; Albrechtsen A.^📨
EJHG(2023)

15 Colonialism in South Africa leaves a lasting legacy of reduced genetic diversity in Cape buffalo
Quinn L.; Garcia-Erill G.; Santander C.; Brüniche-Olsen A.; Liu X.; Sinding M.-H.S.; Heaton M.P.; Smith T.P.L.; Pečnerová P.; Bertola L.D.; Hanghøj K.; Rasmussen M.S.; de Jager D.; Siegismund H.R.; Albrechtsen A.^📨; Heller R.^📨; Moltke I.^📨
Mol. Eco.(2023)

16 Polygenic heterogeneity in antidepressant treatment and placebo response
Nøhr A.K.; Forsingdal A.; Moltke I.; Howes O.D.; Vitezic M.; Albrechtsen A.; Dalby M.
Transl. Psychiatry(2022)

17 Warthog Genomes Resolve an Evolutionary Conundrum and Reveal Introgression of Disease Resistance Genes
Garcia-Erill G.; Jørgensen C.H.F.; Muwanika V.B.; Wang X.; Rasmussen M.S.; De Jong Y.A.; Gaubert P.; Olayemi A.; Salmona J.; Butynski T.M.; Bertola L.D.; Siegismund H.R.; Albrechtsen A.; Heller R.
Mol Biol Evol(2022)

18 Joint identification of sex and sex-linked scaffolds in non-model organisms using low depth sequencing data
Nursyifa C.* ; Brüniche-Olsen A.* ; Garcia-Erill G.; Heller R.^📨; Albrechtsen A.^📨
Mol. Eco. res(2022)

19 Estimation of site frequency spectra from low-coverage sequencing data using stochastic EM reduces overfitting, runtime, and memory usage
Rasmussen M.S.; Garcia-Erill G.; Korneliussen T.S.; Wiuf C.; Albrechtsen A.
Genetics(2022)

20 Efficient approaches for large-scale GWAS with genotype uncertainty
Jørsboe E.; Albrechtsen A.
G3(2022)

21 Life-threatening viral disease in a novel form of autosomal recessive IFNAR2 deficiency in the Arctic
Duncan C.J.A.; Skouboe M.K.; Howarth S.; Hollensen A.K.; Chen R.; Børresen M.L.; Thompson B.J.; Stremenova Spegarova J.; Hatton C.F.; Stæger F.F.; Andersen M.K.; Whittaker J.; Paludan S.R.; Jørgensen S.E.; Thomsen M.K.; Mikkelsen J.G.; Heilmann C.; Buhas D.; Øbro N.F.; Bay J.T.; Marquart H.V.; Teresa de la Morena M.; Klejka J.A.; Hirschfeld M.; Borgwardt L.; Forss I.; Masmas T.; Poulsen A.; Noya F.; Rouleau G.; Hansen T.; Zhou S.; Albrechtsen A.; Alizadehfar R.; Allenspach E.J.; Hambleton S.; Mogensen T.H.
JEM(2022)

22 A large-scale genome-wide gene expression analysis in peripheral blood identifies very few differentially expressed genes related to antidepressant treatment and response in patients with major depressive disorder
Nøhr A.K.; Lindow M.; Forsingdal A.; Demharter S.; Nielsen T.; Buller R.; Moltke I.; Vitezic M.; Albrechtsen A.
Neuropsychopharmacology(2021)

23 Predictors and trajectories of treatment response to SSRIs in patients suffering from PTSD
Nøhr A.K.; Eriksson H.; Hobart M.; Moltke I.; Buller R.; Albrechtsen A.; Lindgreen S.
Psychiatry Res(2021)

24 The genetic history of Greenlandic-European contact
Waples R.K.; Hauptmann A.L.; Seiding I.; Jørsboe E.; Jørgensen M.E.; Grarup N.; Andersen M.K.; Larsen C.V.L.; Bjerregaard P.; Hellenthal G.; Hansen T.^📨; Albrechtsen A.^📨; Moltke I.^📨
Current Biology(2021)

25 Vicariance followed by secondary gene flow in a young gazelle species complex
Garcia-Erill G.; Kjær M.M.; Albrechtsen A.; Siegismund H.R.; Heller R.
Mol. Eco.(2021)

26 Detecting selection in low-coverage high-throughput sequencing data using principal component analysis
Meisner J.; Albrechtsen A.; Hanghøj K.
BMC Bioinformatics(2021)

27 High genetic diversity and low differentiation reflect the ecological versatility of the African leopard
Pečnerová P.; Garcia-Erill G.; Liu X.; Nursyifa C.; Waples R.K.; Santander C.G.; Quinn L.; Frandsen P.; Meisner J.; Stæger F.F.; Rasmussen M.S.; Brüniche-Olsen A.; Hviid Friis Jørgensen C.; da Fonseca R.R.; Siegismund H.R.; Albrechtsen A.; Heller R.; Moltke I.; Hanghøj K.
Current Biology(2021)

28 Physical activity attenuates postprandial hyperglycaemia in homozygous TBC1D4 loss-of-function mutation carriers
Schnurr T.M.; Jørsboe E.; Chadt A.; Dahl-Petersen I.K.; Kristensen J.M.; Wojtaszewski J.F.P.; Springer C.; Bjerregaard P.; Brage S.; Pedersen O.; Moltke I.; Grarup N.; Al-Hasani H.; Albrechtsen A.; Jørgensen M.E.; Hansen T.
Diabetologia(2021)

29 A reference-free approach to analyse RADseq data using standard next generation sequencing toolkits
Heller R.; Nursyifa C.; Garcia-Erill G.; Salmona J.; Chikhi L.; Meisner J.; Korneliussen T.S.; Albrechtsen A.
Mol. Eco. res(2021)

30 Large-scale inference of population structure in presence of missingness using PCA
Meisner J.; Liu S.; Huang M.; Albrechtsen A.
Bioinformatics(2021)

31 NGSremix: A software tool for estimating pairwise relatedness between admixed individuals from next-generation sequencing data
Nøhr A.K.; Hanghøj K.; Garcia-Erill G.; Li Z.; Moltke I.; Albrechtsen A.
G3(2021)

32 Evaluation of model fit of inferred admixture proportions
Garcia-Erill G.; Albrechtsen A.
Mol. Eco. res(2020)

33 Population genomics of the Viking world
Margaryan A.; Lawson D.J.; Sikora M.; Racimo F.; Rasmussen S.; Moltke I.; Cassidy L.M.; Jørsboe E.; Ingason A.; Pedersen M.W.; Korneliussen T.; Wilhelmson H.; Buś M.M.; de Barros Damgaard P.; Martiniano R.; Renaud G.; Bhérer C.; Moreno-Mayar J.V.; Fotakis A.K.; Allen M.; Allmäe R.; Molak M.; Cappellini E.; Scorrano G.; McColl H.; Buzhilova A.; Fox A.; Albrechtsen A.; Schütz B.; Skar B.; Arcini C.; Falys C.; Jonson C.H.; Błaszczyk D.; Pezhemsky D.; Turner-Walker G.; Gestsdóttir H.; Lundstrøm I.; Gustin I.; Mainland I.; Potekhina I.; Muntoni I.M.; Cheng J.; Stenderup J.; Ma J.; Gibson J.; Peets J.; Gustafsson J.; Iversen K.H.; Simpson L.; Strand L.; Loe L.; Sikora M.; Florek M.; Vretemark M.; Redknap M.; Bajka M.; Pushkina T.; Søvsø M.; Grigoreva N.; Christensen T.; Kastholm O.; Uldum O.; Favia P.; Holck P.; Sten S.; Arge S.V.; Ellingvåg S.; Moiseyev V.; Bogdanowicz W.; Magnusson Y.; Orlando L.; Pentz P.; Jessen M.D.; Pedersen A.; Collard M.; Bradley D.G.; Jørkov M.L.; Arneborg J.; Lynnerup N.; Price N.; Gilbert M.T.P.; Allentoft M.E.; Bill J.; Sindbæk S.M.; Hedeager L.; Kristiansen K.; Nielsen R.; Werge T.; Willerslev E.
Nature(2020)

34 Omega-3 fatty acids and risk of cardiovascular disease in Inuit: First prospective cohort study
Senftleber N.K.; Albrechtsen A.; Lauritzen L.; Larsen C.L.; Bjerregaard P.; Diaz L.J.; Rønn P.F.; Jørgensen M.E.
Atherosclerosis(2020)

35 The derived allele of a novel intergenic variant at chromosome 11 associates with lower body mass index and a favorable metabolic phenotype in Greenlanders
Andersen M.K.; Jørsboe E.; Skotte L.; Hanghøj K.; Sandholt C.H.; Moltke I.; Grarup N.; Kern T.; Mahendran Y.; Søborg B.; Bjerregaard P.; Larsen C.V.L.; Dahl-Petersen I.K.; Tiwari H.K.; Feenstra B.; Koch A.; Wiener H.W.; Hopkins S.E.; Pedersen O.; Melbye M.; Boyer B.B.; Jørgensen M.E.; Albrechtsen A.^📨; Hansen T.^📨
PLoS Genetics(2020)

36 Estimating narrow-sense heritability using family data from admixed populations
Athanasiadis G.; Speed D.; Andersen M.K.; Appel E.V.R.; Grarup N.; Brandslund I.; Jørgensen M.E.; Larsen C.V.L.; Bjerregaard P.; Hansen T.; Albrechtsen A.
Heredity(2020)

37 Genetic study of the Arctic CPT1A variant suggests that its effect on fatty acid levels is modulated by traditional Inuit diet
Senftleber N.; Jørgensen M.E.; Jørsboe E.; Imamura F.; Forouhi N.G.; Larsen C.L.; Bjerregaard P.; Hansen T.^📨; Albrechtsen A.^📨
EJHG(2020)

38 A likelihood method for estimating present-day human contamination in ancient male samples using low-depth X-chromosome data
Moreno-Mayar J.V.; Korneliussen T.S.; Dalal J.; Renaud G.; Albrechtsen A.; Nielsen R.; Malaspinas A.-S.
Bioinformatics(2020)

39 DamMet: Ancient methylome mapping accounting for errors, true variants, and post-mortem DNA damage
Hanghøj K.; Renaud G.; Albrechtsen A.; Orlando L.
GigaScience(2019)

40 Ancestry-specific association mapping in admixed populations
Skotte L.; Jørsboe E.; Korneliussen T.S.; Moltke I.; Albrechtsen A.
Genetic Epidemiology(2019)

41 Detection of internal N7-methylguanosine (m7G) RNA modifications by mutational profiling sequencing
Enroth C.; Poulsen L.D.; Iversen S.; Kirpekar F.; Albrechtsen A.; Vinther J.
NAR(2019)

42 Allele frequency-free inference of close familial relationships from genotypes or low-depth sequencing data
Waples R.K.; Albrechtsen A.; Moltke I.
Mol. Eco.(2019)

43 Genomic diversity and novel genome-wide association with fruit morphology in Capsicum, from 746k polymorphic sites
Colonna V.; D’Agostino N.; Garrison E.; Albrechtsen A.; Meisner J.; Facchiano A.; Cardi T.; Tripodi P.
Sci Rep.(2019)

44 Testing for Hardy–Weinberg equilibrium in structured populations using genotype or low-depth next generation sequencing data
Meisner J.; Albrechtsen A.
Mol. Eco. res(2019)

45 Powerful inference with the D-statistic on low-coverage whole-genome data
Soraggi S.; Wiuf C.; Albrechtsen A.
G3(2018)

46 Terminal Pleistocene Alaskan genome reveals first founding population of Native Americans
Moreno-Mayar J.V.; Potter B.A.; Vinner L.; Steinrücken M.; Rasmussen S.; Terhorst J.; Kamm J.A.; Albrechtsen A.; Malaspinas A.-S.; Sikora M.; Reuther J.D.; Irish J.D.; Malhi R.S.; Orlando L.; Song Y.S.; Nielsen R.; Meltzer D.J.; Willerslev E.
Nature(2018)

47 Identification of novel high-impact recessively inherited type 2 diabetes risk variants in the Greenlandic population
Grarup N.; Moltke I.; Andersen M.K.; Bjerregaard P.; Larsen C.V.L.; Dahl-Petersen I.K.; Jørsboe E.; Tiwari H.K.; Hopkins S.E.; Wiener H.W.; Boyer B.B.; Linneberg A.; Pedersen O.; Jørgensen M.E.; Albrechtsen A.; Hansen T.
Diabetologia(2018)

48 Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes
Grarup N.; Moltke I.; Andersen M.K.; Dalby M.; Vitting-Seerup K.; Kern T.; Mahendran Y.; Jørsboe E.; Larsen C.V.L.; Dahl-Petersen I.K.; Gilly A.; Suveges D.; Dedoussis G.; Zeggini E.; Pedersen O.; Andersson R.; Bjerregaard P.; Jørgensen M.E.; Albrechtsen A.^📨; Hansen T.^📨
Nature Genetics(2018)

49 Genomic Analyses from Non-invasive Prenatal Testing Reveal Genetic Associations, Patterns of Viral Infections, and Chinese Population History
Liu S.; Huang S.; Chen F.; Zhao L.; Yuan Y.; Francis S.S.; Fang L.; Li Z.; Lin L.; Liu R.; Zhang Y.; Xu H.; Li S.; Zhou Y.; Davies R.W.; Liu Q.; Walters R.G.; Lin K.; Ju J.; Korneliussen T.; Yang M.A.; Fu Q.; Wang J.; Zhou L.; Krogh A.; Zhang H.; Wang W.; Chen Z.; Cai Z.; Yin Y.; Yang H.; Mao M.; Shendure J.; Wang J.^📨; Albrechtsen A.^📨; Jin X.^📨; Nielsen R.^📨; Xu X.^📨
Cell(2018)

50 Inferring population structure and admixture proportions in low-depth NGS data
Meisner J.; Albrechtsen A.
Genetics(2018)

51 Ancient genomes revisit the ancestry of domestic and Przewalski’s horses
Gaunitz C.; Fages A.; Hanghøj K.; Albrechtsen A.; Khan N.; Schubert M.; Seguin-Orlando A.; Owens I.J.; Felkel S.; Bignon-Lau O.; Damgaard P.D.B.; Mittnik A.; Mohaseb A.F.; Davoudi H.; Alquraishi S.; Alfarhan A.H.; Al-Rasheid K.A.S.; Crubézy E.; Benecke N.; Olsen S.; Brown D.; Anthony D.; Massy K.; Pitulko V.; Kasparov A.; Brem G.; Hofreiter M.; Mukhtarova G.; Baimukhanov N.; Lõugas L.; Onar V.; Stockhammer P.W.; Krause J.; Boldgiv B.; Undrakhbold S.; Erdenebaatar D.; Lepetz S.; Mashkour M.; Ludwig A.; Wallner B.; Merz V.; Merz I.; Zaibert V.; Willerslev E.; Librado P.; Outram A.K.; Orlando L.
Science(2018)

52 A southern African origin and cryptic structure in the highly mobile plains zebra
Pedersen C.-E.T.; Albrechtsen A.; Etter P.D.; Johnson E.A.; Orlando L.; Chikhi L.; Siegismund H.R.; Heller R.
Nature E&E(2018)

53 Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population
Appel E.V.R.; Moltke I.; Jørgensen M.E.; Bjerregaard P.; Linneberg A.; Pedersen O.; Albrechtsen A.; Hansen T.; Grarup N.
EJHG(2018)

54 Genetic architecture of obesity and related metabolic traits — recent insights from isolated populations
Andersen M.K.; Grarup N.; Moltke I.; Albrechtsen A.; Hansen T.
Curr Opin Genetics Dev(2018)

55 Archaic adaptive introgression in TBX15/WARS2
Racimo F.; Gokhman D.; Fumagalli M.; Ko A.; Hansen T.; Moltke I.; Albrechtsen A.; Carmel L.; Huerta-Sanchez E.; Nielsen R.
Mol Biol Evol(2017)

56 Founder Effect of the RETC611Y Mutation in Multiple Endocrine Neoplasia 2A in Denmark: A Nationwide Study
Mathiesen J.S.; Kroustrup J.P.; Vestergaard P.; Stochholm K.; Poulsen P.L.; Rasmussen A.K.; Feldt-Rasmussen U.; Gaustadnes M.; Ørntoft T.F.; Rossing M.; Nielsen F.C.; Albrechtsen A.; Brixen K.; Godballe C.; Frederiksen A.L.
Thyroid(2017)

57 FastNGSadmix: Admixture proportions and principal component analysis of a single NGS sample
Jørsboe E.; Hanghøj K.; Albrechtsen A.
Bioinformatics(2017)

58 Ancient genomes show social and reproductive behavior of early Upper Paleolithic foragers
Sikora M.; Seguin-Orlando A.; Sousa V.C.; Albrechtsen A.; Korneliussen T.; Ko A.; Rasmussen S.; Dupanloup I.; Nigst P.R.; Bosch M.D.; Renaud G.; Allentoft M.E.; Margaryan A.; Vasilyev S.V.; Veselovskaya E.V.; Borutskaya S.B.; Deviese T.; Comeskey D.; Higham T.; Manica A.; Foley R.; Meltzer D.J.; Nielsen R.; Excoffier L.; Lahr M.M.; Orlando L.; Willerslev E.
Science(2017)

59 Genetic screening of the FLCN gene identify six novel variants and a Danish founder mutation
Rossing M.; Albrechtsen A.; Skytte A.-B.; Jensen U.B.; Ousager L.B.; Gerdes A.-M.; Nielsen F.C.; Hansen T.V.
J Hum genet(2017)

60 Ancient genomic changes associated with domestication of the horse
Librado P.; Gamba C.; Gaunitz C.; Der Sarkissian C.; Pruvost M.; Albrechtsen A.; Fages A.; Khan N.; Schubert M.; Jagannathan V.; Serres-Armero A.; Kuderna L.F.K.; Povolotskaya I.S.; Seguin-Orlando A.; Lepetz S.; Neuditschko M.; Thèves C.; Alquraishi S.; Alfarhan A.H.; Al-Rasheid K.; Rieder S.; Samashev Z.; Francfort H.-P.; Benecke N.; Hofreiter M.; Ludwig A.; Keyser C.; Marques-Bonet T.; Ludes B.; Crubézy E.; Leeb T.; Willerslev E.; Orlando L.
Science(2017)

61 The effect of an extreme and prolonged population bottleneck on patterns of deleterious variation: Insights from the Greenlandic Inuit
Pedersen C.-E.T.; Lohmueller K.E.; Grarup N.; Bjerregaard P.; Hansen T.; Siegismund H.R.; Moltke I.; Albrechtsen A.
Genetics(2017)

62 Weighting sequence variants based on their annotation increases power of whole-genome association studies
Sveinbjornsson G.; Albrechtsen A.; Zink F.; Gudjonsson S.A.; Oddson A.; Másson G.; Holm H.; Kong A.; Thorsteinsdottir U.; Sulem P.; Gudbjartsson D.F.; Stefansson K.
Nature Genetics(2016)

63 Estimating IBD tracts from low coverage NGS data
Vieira F.G.; Albrechtsen A.; Nielsen R.
Bioinformatics(2016)

64 Genetics of Type 2 Diabetes: the Power of Isolated Populations
Andersen M.K.; Pedersen C.-E.T.; Moltke I.; Hansen T.; Albrechtsen A.; Grarup N.
Current Diabetes Reports(2016)

65 Identification of Novel Genetic Determinants of Erythrocyte Membrane Fatty Acid Composition among Greenlanders
Andersen M.K.; Jørsboe E.; Sandholt C.H.; Grarup N.; Jørgensen M.E.; Færgeman N.J.; Bjerregaard P.; Pedersen O.; Moltke I.; Hansen T.; Albrechtsen A.
PLoS Genetics(2016)

66 Next-generation biology: Sequencing and data analysis approaches for non-model organisms
da Fonseca R.R.; Albrechtsen A.; Themudo G.E.; Ramos-Madrigal J.; Sibbesen J.A.; Maretty L.; Zepeda-Mendoza M.L.; Campos P.F.; Heller R.; Pereira R.J.
Mar Genomics(2016)

67 A genomic history of Aboriginal Australia
Malaspinas A.-S.; Westaway M.C.; Muller C.; Sousa V.C.; Lao O.; Alves I.; Bergström A.; Athanasiadis G.; Cheng J.Y.; Crawford J.E.; Heupink T.H.; MacHoldt E.; Peischl S.; Rasmussen S.; Schiffels S.; Subramanian S.; Wright J.L.; Albrechtsen A.; Barbieri C.; Dupanloup I.; Eriksson A.; Margaryan A.; Moltke I.; Pugach I.; Korneliussen T.S.; Levkivskyi I.P.; Moreno-Mayar J.V.; Ni S.; Racimo F.; Sikora M.; Xue Y.; Aghakhanian F.A.; Brucato N.; Brunak Sø.; Campos P.F.; Clark W.; Ellingvåg S.; Fourmile G.; Gerbault P.; Injie D.; Koki G.; Leavesley M.; Logan B.; Lynch A.; Matisoo-Smith E.A.; McAllister P.J.; Mentzer A.J.; Metspalu M.; Migliano A.B.; Murgha L.; Phipps M.E.; Pomat W.; Reynolds D.; Ricaut F.-X.; Siba P.; Thomas M.G.; Wales T.; Wall C.M.; Oppenheimer S.J.; Tyler-Smith C.; Durbin R.; Dortch J.; Manica A.; Schierup M.H.; Foley R.A.; Lahr M.M.; Bowern C.; Wall J.D.; Mailund T.; Stoneking M.; Nielsen R.; Sandhu M.S.; Excoffier L.; Lambert D.M.; Willerslev E.
Nature(2016)

68 Diabetes in population isolates: Lessons from Greenland
Grarup N.; Moltke I.; Albrechtsen A.; Hansen T.
Review of Diabetic Studies(2015)

69 Evolutionary genomics and conservation of the endangered Przewalski’s horse
Der Sarkissian C.; Ermini L.; Schubert M.; Yang M.A.; Librado P.; Fumagalli M.; Jónsson H.; Bar-Gal G.K.; Albrechtsen A.; Vieira F.G.; Petersen B.; Ginolhac A.; Seguin-Orlando A.; Magnussen K.; Fages A.; Gamba C.; Lorente-Galdos B.; Polani S.; Steiner C.; Neuditschko M.; Jagannathan V.; Feh C.; Greenblatt C.L.; Ludwig A.; Abramson N.I.; Zimmermann W.; Schafberg R.; Tikhonov A.; Sicheritz-Ponten T.; Willerslev E.; Marques-Bonet T.; Ryder O.A.; McCue M.; Rieder S.; Leeb T.; Slatkin M.; Orlando L.
Current Biology(2015)

70 Partial USH2A deletions contribute to Usher syndrome in Denmark
Dad S.; Rendtorff N.D.; Kann E.; Albrechtsen A.; Mehrjouy M.M.; Bak M.; Tommerup N.; Tranebjærg L.; Rosenberg T.; Jensen H.; Møller L.B.
EJHG(2015)

71 Uncovering the genetic history of the present-day greenlandic population
Moltke I.; Fumagalli M.; Korneliussen T.S.; Crawford J.E.; Bjerregaard P.; Jørgensen M.E.; Grarup N.; Gulløv H.C.; Linneberg A.; Pedersen O.; Hansen T.^📨; Nielsen R.^📨; Albrechtsen A.^📨
AJHG(2015)

72 Tracking the origins of Yakutian horses and the genetic basis for their fast adaptation to subarctic environments
Librado P.; Der Sarkissian C.; Ermini L.; Schubert M.; Jónsson H.; Albrechtsen A.; Fumagalli M.; Yang M.A.; Gamba C.; Seguin-Orlando A.; Mortensen C.D.; Petersen B.; Hoove C.A.; Lorente-Galdos B.; Nedoluzhko A.; Boulygina E.; Tsygankova S.; Neuditschko M.; Jagannathan V.; Thèves C.; Alfarhan A.H.; Alquraishi S.A.; Al-Rasheid K.A.S.; Sicheritz-Ponten T.; Popov R.; Grigoriev S.; Alekseev A.N.; Rubin E.M.; McCue M.; Rieder S.; Leeb T.; Tikhonov A.; Crubézy E.; Slatkin M.; Marques-Bonet T.; Nielsen R.; Willerslev E.; Kantanen J.; Prokhortchouk E.; Orlando L.
PNAS(2015)

73 The ancestry and affiliations of Kennewick Man
Rasmussen M.; Sikora M.; Albrechtsen A.; Korneliussen T.S.; Moreno-Mayar J.V.; Poznik G.D.; Zollikofer C.P.E.; Ponce De León M.S.; Allentoft M.E.; Moltke I.; Jónsson H.; Valdiosera C.; Malhi R.S.; Orlando L.; Bustamante C.D.; Stafford T.W., Jr.; Meltzer D.J.; Nielsen R.; Willerslev E.
Nature(2015)

74 The origin and evolution of maize in the Southwestern United States
Da Fonseca R.R.; Smith B.D.; Wales N.; Cappellini E.; Skoglund P.; Fumagalli M.; Samaniego J.A.; Carøe C.; Ávila-Arcos M.C.; Hufnagel D.E.; Korneliussen T.S.; Vieira F.G.; Jakobsson M.; Arriaza B.; Willerslev E.; Nielsen R.; Hufford M.B.; Albrechtsen A.; Ross-Ibarra J.; Gilbert M.T.P.
Nature Plants(2015)

75 Greenlandic Inuit show genetic signatures of diet and climate adaptation
Fumagalli M.; Moltke I.; Grarup N.; Racimo F.; Bjerregaard P.; Jørgensen M.E.; Korneliussen T.S.; Gerbault P.; Skotte L.; Linneberg A.; Christensen C.; Brandslund I.; Jørgensen T.; Huerta-Sánchez E.; Schmidt E.B.; Pedersen O.; Hansen T.^📨; Albrechtsen A.^📨; Nielsen R.^📨
Science(2015)

76 Genomic evidence for the Pleistocene and recent population history of Native Americans
Raghavan M.; Steinrücken M.; Harris K.; Schiffels S.; Rasmussen S.; DeGiorgio M.; Albrechtsen A.; Valdiosera C.; Ávila-Arcos M.C.; Malaspinas A.-S.; … Manica A.; Durbin R.; Bustamante C.D.; Song Y.S.; Nielsen R.; Willerslev E.
Science(2015)

77 Genomic structure in Europeans dating back at least 36,200 years
Seguin-Orlando A.; Korneliussen T.S.; Sikora M.; Malaspinas A.-S.; Manica A.; Moltke I.; Albrechtsen A.; Ko A.; Margaryan A.; Moiseyev V.; Goebel T.; Westaway M.; Lambert D.; Khartanovich V.; Wall J.D.; Nigst P.R.; Foley R.A.; Lahr M.M.; Nielsen R.; Orlando L.; Willerslev E.
Science(2014)

78 The genetic prehistory of the New World Arctic
Raghavan M.; DeGiorgio M.; Albrechtsen A.; Moltke I.; Skoglund P.; Korneliussen T.S.; Grønnow B.; Appelt M.; Gulløv H.C.; Friesen T.M.; Fitzhugh W.; Malmström H.; Rasmussen S.; Olsen J.; Melchior L.; Fuller B.T.; Fahrni S.M.; Stafford T., Jr.; Grimes V.; Renouf M.A.P.; Cybulski J.; Lynnerup N.; Lahr M.M.; Britton K.; Knecht R.; Arneborg J.; Metspalu M.; Cornejo O.E.; Malaspinas A.-S.; Wang Y.; Rasmussen M.; Raghavan V.; Hansen T.V.O.; Khusnutdinova E.; Pierre T.; Dneprovsky K.; Andreasen C.; Lange H.; Hayes M.G.; Coltrain J.; Spitsyn V.A.; Götherström A.; Orlando L.; Kivisild T.; Villems R.; Crawford M.H.; Nielsen F.C.; Dissing J.; Heinemeier J.; Meldgaard M.; Bustamante C.; O’Rourke D.H.; Jakobsson M.; Gilbert M.T.P.; Nielsen R.; Willerslev E.
Science(2014)

79 Speciation with gene flow in equids despite extensive chromosomal plasticity
Jónsson H.; Schubert M.; Seguin-Orlando A.; Ginolhac A.; Petersen L.; Fumagalli M.; Albrechtsen A.; Petersen B.; Korneliussen T.S.; Vilstrup J.T.; Lear T.; Myka J.L.; Lundquist J.; Miller D.C.; Alfarhan A.H.; Alquraishi S.A.; Al-Rasheid K.A.S.; Stagegaard J.; Strauss G.; Bertelsen M.F.; Sicheritz-Ponten T.; Antczak D.F.; Bailey E.; Nielsen R.; Willerslev E.; Orlando L.
PNAS(2014)

80 ANGSD: Analysis of Next Generation Sequencing Data
Korneliussen T.S.; Albrechtsen A.; Nielsen R.
BMC Bioinformatics(2014)

81 RelateAdmix: A software tool for estimating relatedness between admixed individuals
Moltke I.; Albrechtsen A.
Bioinformatics(2014)

82 Upper palaeolithic Siberian genome reveals dual ancestry of native Americans
Raghavan M.; Skoglund P.; Graf K.E.; Metspalu M.; Albrechtsen A.; Moltke I.; Rasmussen S.; Stafford T.W., Jr.; Orlando L.; Metspalu E.; Karmin M.; Tambets K.; Rootsi S.; Mägi R.; Campos P.F.; Balanovska E.; Balanovsky O.; Khusnutdinova E.; Litvinov S.; Osipova L.P.; Fedorova S.A.; Voevoda M.I.; Degiorgio M.; Sicheritz-Ponten T.; Brunak Sø.; Demeshchenko S.; Kivisild T.; Villems R.; Nielsen R.; Jakobsson M.; Willerslev E.
Nature(2014)

83 Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil
Malaspinas A.-S.; Lao O.; Schroeder H.; Rasmussen M.; Raghavan M.; Moltke I.; Campos P.F.; Sagredo F.S.; Rasmussen S.; Gonçalves V.F.; Albrechtsen A.; Allentoft M.E.; Johnson P.L.F.; Li M.; Reis S.; Bernardo D.V.; Degiorgio M.; Duggan A.T.; Bastos M.; Wang Y.; Stenderup J.; Moreno-Mayar J.V.; Brunak Sø.; Sicheritz-Ponten T.; Hodges E.; Hannon G.J.; Orlando L.; Price T.D.; Jensen J.D.; Nielsen R.; Heinemeier J.; Olsen J.; Rodrigues-Carvalho C.; Lahr M.M.; Neves W.A.; Kayser M.; Higham T.; Stoneking M.; Pena S.D.J.; Willerslev E.
Current Biology(2014)

84 Prehistoric genomes reveal the genetic foundation and cost of horse domestication
Schubert M.; Jónsson H.; Chang D.; Der Sarkissian C.; Ermini L.; Ginolhac A.; Albrechtsen A. … Nielsen R.; Excoffier L.; Willerslev E.; Shapiro B.; Orlando L.
PNAS(2014)

85 Genetic and environmental determinants of 25-hydroxyvitamin D levels in multiple sclerosis
Laursen J.H.; Søndergaard H.B.; Albrechtsen A.; Frikke-Schmidt R.; Koch-Henriksen N.; Soelberg Sørensen P.; Sellebjerg F.; Oturai A.
Multiple Sclerosis(2014)

86 Variation and association to diabetes in 2000 full mtDNA sequences mined from an exome study in a Danish population
Li S.; Besenbacher S.; Li Y.; Kristiansen K.; Grarup N.; Albrechtsen A.; Sparsø T.; Korneliussen T.; Hansen T.; Wang J.; Nielsen R.; Pedersen O.; Bolund L.; Schierup M.H.
EJHG(2014)

87 The genome of a Late Pleistocene human from a Clovis burial site in western Montana
Rasmussen M.; Anzick S.L.; Waters M.R.; Skoglund P.; Degiorgio M.; Stafford Jr. T.W.; Rasmussen S.; Moltke I.; Albrechtsen A.; Doyle S.M.; Poznik G.D.; Gudmundsdottir V.; Yadav R.; Malaspinas A.-S.; Samuel Stockton White V.; Allentoft M.E.; Cornejo O.E.; Tambets K.; Eriksson A.; Heintzman P.D.; Karmin M.; Korneliussen T.S.; Meltzer D.J.; Pierre T.L.; Stenderup J.; Saag L.; Warmuth V.M.; Lopes M.C.; Malhi R.S.; Brunak Sø.; Sicheritz-Ponten T.; Barnes I.; Collins M.; Orlando L.; Balloux F.; Manica A.; Gupta R.; Metspalu M.; Bustamante C.D.; Jakobsson M.; Nielsen R.; Willerslev E.
Nature(2014)

88 A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes
Moltke I.; Grarup N.; Jørgensen M.E.; Bjerregaard P.; Treebak J.T.; Fumagalli M.; Korneliussen T.S.; Andersen M.A.; Nielsen T.S.; Krarup N.T.; Gjesing A.P.; Zierath J.R.; Linneberg A.; Wu X.; Sun G.; Jin X.; Al-Aama J.; Wang J.; Borch-Johnsen K.; Pedersen O.; Nielsen R.^📨; Albrechtsen A.^📨; Hansen T.^📨
Nature(2014)

89 Genome-Wide Association Study of Genetic Variants in LPS-Stimulated IL-6, IL-8, IL-10, IL-1ra and TNF-α Cytokine Response in a Danish Cohort
Larsen M.H.; Albrechtsen A.; Thørner L.W.; Werge T.; Hansen T.; Gether U.; Haastrup E.; Ullum H.
PLoS ONE(2013)

90 Exome sequencing-driven discovery of coding polymorphisms associated with common metabolic phenotypes
Albrechtsen A.; Grarup N.; Li Y.; Sparsø T.; Tian G.; Cao H.; Jiang T.; Kim S.Y.; Korneliussen T.; Li Q.; Nie C.; Wu R.; Skotte L.; Morris A.P.; Ladenvall C.; Cauchi S.; Stančáková A.; Andersen G.; Astrup A.; Banasik K.; Bennett A.J.; Bolund L.; Charpentier G.; Chen Y.; Dekker J.M.; Doney A.S.F.; Dorkhan M.; Forsen T.; Frayling T.M.; Groves C.J.; Gui Y.; Hallmans G.; Hattersley A.T.; He K.; Hitman G.A.; Holmkvist J.; Huang S.; Jiang H.; Jin X.; Justesen J.M.; Kristiansen K.; Kuusisto J.; Lajer M.; Lantieri O.; Li W.; Liang H.; Liao Q.; Liu X.; Ma T.; Ma X.; Manijak M.P.; Marre M.; Mokrosiński J.; Morris A.D.; Mu B.; Nielsen A.A.; Nijpels G.; Nilsson P.; Palmer C.N.A.; Rayner N.W.; Renström F.; Ribel-Madsen R.; Robertson N.; Rolandsson O.; Rossing P.; Schwartz T.W.; Slagboom P.E.; Sterner M.; Tang M.; Tarnow L.; Tuomi T.; Van’T Riet E.; Van Leeuwen N.; Varga T.V.; Vestmar M.A.; Walker M.; Wang B.; Wang Y.; Wu H.; Xi F.; Yengo L.; Yu C.; Zhang X.; Zhang J.; Zhang Q.; Zhang W.; Zheng H.; Zhou Y.; Altshuler D.; ‘T Hart L.M.; Franks P.W.; Balkau B.; Froguel P.; McCarthy M.I.; Laakso M.; Groop L.; Christensen C.; Brandslund I.; Lauritzen T.; Witte D.R.; Linneberg A.; Jørgensen T.; Hansen T.; Wang J.; Nielsen R.; Pedersen O.
Diabetologia(2013)

91 Estimating inbreeding coefficients from NGS data: Impact on genotype calling and allele frequency estimation
Vieira F.G.; Fumagalli M.; Albrechtsen A.; Nielsen R.
Genome Research(2013)

92 Recalibrating equus evolution using the genome sequence of an early Middle Pleistocene horse
Orlando L.; Ginolhac A.; Zhang G.; Froese D.; Albrechtsen A.; Stiller M.; Schubert M.; Cappellini E.; Petersen B.; Moltke I.; Johnson P.L.F.; Fumagalli M.; Vilstrup J.T.; Raghavan M.; Korneliussen T.; Malaspinas A.-S.; Vogt J.; Szklarczyk D.; Kelstrup C.D.; Vinther J.; Dolocan A.; Stenderup J.; Velazquez A.M.V.; Cahill J.; Rasmussen M.; Wang X.; Min J.; Zazula G.D.; Seguin-Orlando A.; Mortensen C.; Magnussen K.; Thompson J.F.; Weinstock J.; Gregersen K.; Røed K.H.; Eisenmann V.; Rubin C.J.; Miller D.C.; Antczak D.F.; Bertelsen M.F.; Brunak Sø.; Al-Rasheid K.A.S.; Ryder O.; Andersson L.; Mundy J.; Krogh A.; Gilbert M.T.P.; Kjær K.; Sicheritz-Ponten T.; Jensen L.J.; Olsen J.V.; Hofreiter M.; Nielsen R.; Shapiro B.; Wang J.; Willerslev E.
Nature(2013)

93 Calculation of Tajima’s D and other neutrality test statistics from low depth next-generation sequencing data
Korneliussen T.S.; Moltke I.; Albrechtsen A.; Nielsen R.
BMC Bioinformatics(2013)

94 Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes
Lohmueller K.E.; Sparsø T.; Li Q.; Andersson E.; Korneliussen T.; Albrechtsen A.; Banasik K.; Grarup N.; Hallgrimsdottir I.; Kiil K.; Kilpeläinen T.O.; Krarup N.T.; Pers T.H.; Sanchez G.; Hu Y.; Degiorgio M.; Jørgensen T.; Sandbæk A.; Lauritzen T.; Brunak Sø.; Kristiansen K.; Li Y.; Hansen T.; Wang J.; Nielsen R.; Pedersen O.
AJHG(2013)

95 Genetic Architecture of Vitamin B12 and Folate Levels Uncovered Applying Deeply Sequenced Large Datasets
Grarup N.; Sulem P.; Sandholt C.H.; Thorleifsson G.; Ahluwalia T.S.; Steinthorsdottir V.; Bjarnason H.; Gudbjartsson D.F.; Magnusson O.T.; Sparsø T.; Albrechtsen A.; Kong A.; Masson G.; Tian G.; Cao H.; Nie C.; Kristiansen K.; Husemoen L.L.; Thuesen B.; Li Y.; Nielsen R.; Linneberg A.; Olafsson I.; Eyjolfsson G.I.; Jørgensen T.; Wang J.; Hansen T.; Thorsteinsdottir U.; Stefánsson K.; Pedersen O.
PLoS Genetics(2013)

96 Quantifying population genetic differentiation from next-generation sequencing data
Fumagalli M.; Vieira F.G.; Korneliussen T.S.; Linderoth T.; Huerta-Sánchez E.; Albrechtsen A.; Nielsen R.
Genetics(2013)

97 Estimating individual admixture proportions from next generation sequencing data
Skotte L.; Korneliussen T.S.; Albrechtsen A.
Genetics(2013)

98 SNP calling, genotype calling, and sample allele frequency estimation from new-generation sequencing data
Nielsen R.; Korneliussen T.; Albrechtsen A.; Li Y.; Wang J.
PLoS ONE(2012)

99 Association Testing for Next-Generation Sequencing Data Using Score Statistics
Skotte L.; Korneliussen T.S.; Albrechtsen A.
Genetic Epidemiology(2012)

100 Natural selection affects multiple aspects of genetic variation at putatively neutral sites across the human genome
Lohmueller K.E.; Albrechtsen A.; Li Y.; Kim S.Y.; Korneliussen T.; Vinckenbosch N.; Tian G.; Huerta-Sanchez E.; Feder A.F.; Grarup N.; Jørgensen T.; Jiang T.; Witte D.R.; Sandbæk A.; Hellmann I.; Lauritzen T.; Hansen T.; Pedersen O.; Wang J.; Nielsen R.
PLoS Genetics(2011)

101 A method for detecting IBD regions simultaneously in multiple individuals - With applications to disease genetics
Moltke I.; Albrechtsen A.; Hansen T.V.O.; Nielsen F.C.; Nielsen R.
Genome Research(2011)

102 An aboriginal Australian genome reveals separate human dispersals into Asia
Rasmussen M.; Guo X.; Wang Y.; Lohmueller K.E.; Rasmussen S.; Albrechtsen A.; Skotte L.; Lindgreen S.; Metspalu M.; Jombart T.; Kivisild T.; Zhai W.; Eriksson A.; Manica A.; Orlando L.; De La Vega F.M.; Tridico S.; Metspalu E.; Nielsen K.; Ávila-Arcos M.C.; Víctor Moreno-Mayar J.; Muller C.; Dortch J.; Gilbert M.T.P.; Lund O.; Wesolowska A.; Karmin M.; Weinert L.A.; Wang B.; Li J.; Tai S.; Xiao F.; Hanihara T.; Van Driem G.; Jha A.R.; Ricaut F.-X.; De Knijff P.; Migliano A.B.; Romero I.G.; Kristiansen K.; Lambert D.M.; Brunak S.; Forster P.; Brinkmann B.; Nehlich O.; Bunce M.; Richards M.; Gupta R.; Bustamante C.D.; Krogh A.; Foley R.A.; Lahr M.M.; Balloux F.; Sicheritz-Pontén T.; Villems R.; Nielsen R.; Wang J.; Willerslev E.
Science(2011)

103 Estimation of allele frequency and association mapping using next-generation sequencing data
Kim S.Y.; Lohmueller K.E.; Albrechtsen A.; Li Y.; Korneliussen T.; Tian G.; Grarup N.; Jiang T.; Andersen G.; Witte D.; Jorgensen T.; Hansen T.; Pedersen O.; Wang J.; Nielsen R.
BMC Bioinformatics(2011)

104 Genotype and SNP calling from next-generation sequencing data
Nielsen R.; Paul J.S.; Albrechtsen A.; Song Y.S.
Nature Reviews Genetics(2011)

105 Ancient human genome sequence of an extinct Palaeo-Eskimo
Rasmussen M.; Li Y.; Lindgreen S.; Pedersen J.S.; Albrechtsen A.; Moltke I.; Metspalu M.; Metspalu E.; Kivisild T.; Gupta R.; Bertalan M.; Nielsen K.; Gilbert M.T.P.; Wang Y.; Raghavan M.; Campos P.F.; Kamp H.M.; Wilson A.S.; Gledhill A.; Tridico S.; Bunce M.; Lorenzen E.D.; Binladen J.; Guo X.; Zhao J.; Zhang X.; Zhang H.; Li Z.; Chen M.; Orlando L.; Kristiansen K.; Bak M.; Tommerup N.; Bendixen C.; Pierre T.L.; Gronnow B.; Meldgaard M.; Andreasen C.; Fedorova S.A.; Osipova L.P.; Higham T.F.G.; Ramsey C.B.; Hansen T.V.O.; Nielsen F.C.; Crawford M.H.; Brunak S.; Sicheritz-Pont́n T.; Villems R.; Nielsen R.; Krogh A.; Wang J.; Willerslev E.
Nature(2010)

106 Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Gjesing A.P.; Larsen L.H.; Torekov S.S.; Hainerová I.A.; Kapur R.; Johansen A.; Albrechtsen A.; Boj S.; Holst B.; Harper A.; Urhammer S.A.; Borch-Johnsen K.; Pisinger C.; Echwald S.M.; Eiberg H.; Astrup A.; Lebl J.; Ferrer J.; Schwartz T.W.; Hansen T.; Pedersen O.
PLoS ONE(2010)

107 Ascertainment biases in SNP chips affect measures of population divergence
Albrechtsen A.; Nielsen F.C.; Nielsen R.
Mol Biol Evol(2010)

108 Identification of a novel BRCA1 nucleotide 4803delCC/c.4684delCC mutation and a nucleotide 249T>A/c.130T>A (p.Cys44Ser) mutation in two Greenlandic Inuit families: Implications for genetic screening of Greenlandic Inuit families with high risk for breast and/or ovarian cancer
Hansen T.V.O.; Jønson L.; Albrechtsen A.; Steffensen A.Y.; Bergsten E.; Myrhøj T.; Ejlertsen B.; Nielsen F.C.
Breast Cancer Res Treat(2010)

109 Natural selection and the distribution of identity-by-descent in the human genome
Albrechtsen A.; Moltke I.; Nielsen R.
Genetics(2010)

110 Interleukin-6 autoantibodies are involved in the pathogenesis of a subset of type 2 diabetes
Fosgerau K.; Galle P.; Hansen T.; Albrechtsen A.; De Lemos Rieper C.; Pedersen B.K.; Larsen L.K.; Thomsen A.R.; Pedersen O.; Hansen M.B.; Steensberg A.
Journal of Endocrinology(2010)

111 Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
Li Y.; Vinckenbosch N.; Tian G.; Huerta-Sanchez E.; Jiang T.; Jiang H.; Albrechtsen A.; Andersen G.; Cao H.; Korneliussen T.; Grarup N.; Guo Y.; Hellman I.; Jin X.; Li Q.; Liu J.; Liu X.; Sparsø T.; Tang M.; Wu H.; Wu R.; Yu C.; Zheng H.; Astrup A.; Bolund L.; Holmkvist J.; Jørgensen T.; Kristiansen K.; Schmitz O.; Schwartz T.W.; Zhang X.; Li R.; Yang H.; Wang J.; Hansen T.; Pedersen O.; Nielsen R.; Wang J.
Nature Genetics(2010)

112 Segregation distortion in chicken and the evolutionary consequences of female meiotic drive in birds
Axelsson E.; Albrechtsen A.; Van A.P.; Li L.; Megens H.J.; Vereijken A.L.J.; Crooijmans R.P.M.A.; Groenen M.A.M.; Ellegren H.; Willerslev E.; Nielsen R.
Heredity(2010)

113 Identification of a novel locus for a USH3 like syndrome combined with congenital cataract
Dad S.; Østergaard E.; Thykjær T.; Albrectsen A.; Ravn K.; Rosenberg T.; Møller L.B.
Clinical Genetics(2010)

114 Combined analyses of 20 common obesity susceptibility variants
Sandholt C.H.; Sparsø T.; Grarup N.; Albrechtsen A.; Almind K.; Hansen L.; Toft U.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetes(2010)

115 Darwinian and demographic forces affecting human protein coding genes
Nielsen R.; Hubisz M.J.; Hellmann I.; Torgerson D.; Andrés A.M.; Albrechtsen A.; Gutenkunst R.; Adams M.D.; Cargill M.; Boyko A.; Indap A.; Bustamante C.D.; Clark A.G.
Genome Research(2009)

116 Functional SOCS1 polymorphisms are associated with variation in obesity in whites
Gylvin T.; Ek J.; Nolsøe R.; Albrechtsen A.; Andersen G.; Bergholdt R.; Brorsson C.; Bang-Berthelsen C.H.; Hansen T.; Karlsen A.E.; Billestrup N.; Borch-Johnsen K.; Jørgensen T.; Pedersen O.; Mandrup-Poulsen T.; Nerup J.; Pociot F.
Diabetes Obes Metab(2009)

117 The validation and assessment of machine learning: A game of prediction from high-dimensional data
Pers T.H.; Albrechtsen A.; Holst C.; Sørensen T.I.A.; Gerds T.A.
PLoS ONE(2009)

118 Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction
Sparsø T.; Grarup N.; Andreasen C.; Albrechtsen A.; Holmkvist J.; Andersen G.; Jørgensen T.; Borch-Johnsen K.; Sandbæk A.; Lauritzen T.; Madsbad S.; Hansen T.; Pedersen O.
Diabetologia(2009)

119 A variant in the G6PC2/ABCB11 locus is associated with increased fasting plasma glucose, increased basal hepatic glucose production and increased insulin release after oral and intravenous glucose loads
Rose C.S.; Grarup N.; Krarup N.T.; Poulsen P.; Wegner L.; Nielsen T.; Banasik K.; Færch K.; Andersen G.; Albrechtsen A.; Borch-Johnsen K.; Clausen J.O.; Jørgensen T.; Vaag A.; Pedersen O.; Hansen T.
Diabetologia(2009)

120 Large BRCA1 and BRCA2 genomic rearrangements in Danish high risk breast-ovarian cancer families
Hansen T.V.O.; Jønson L.; Albrechtsen A.; Andersen M.K.; Ejlertsen B.; Nielsen F.C.
Breast Cancer Res Treat(2009)

121 Relatedness mapping and tracts of relatedness for genome-wide data in the presence of linkage disequilibrium
Albrechtsen A.; Korneliussen T.S.; Moltke I.; van Overseem Hansen T.; Nielsen F.C.; Nielsen R.
Genetic Epidemiology(2009)

122 Genetic variant near IRS1 is associated with type 2 diabetes, insulin resistance and hyperinsulinemia
Rung J.; Cauchi S.; Albrechtsen A.*; Shen L.; Rocheleau G.; Cavalcanti-Proença C.; Bacot F.; Balkau B.; Belisle A.; Borch-Johnsen K.; Charpentier G.; Dina C.; Durand E.; Elliott P.; Hadjadj S.; Järvelin M.-R.; Laitinen J.; Lauritzen T.; Marre M.; Mazur A.; Meyre D.; Montpetit A.; Pisinger C.; Posner B.; Poulsen P.; Pouta A.; Prentki M.; Ribel-Madsen R.; Ruokonen A.; Sandbaek A.; Serre D.; Tichet J.; Vaxillaire M.; Wojtaszewski J.F.P.; Vaag A.; Hansen T.; Polychronakos C.; Pedersen O.; Froguel P.; Sladek R.
Nature Genetics(2009)

123 A common Greenlandic Inuit BRCA1 RING domain founder mutation
Hansen T.V.O.; Ejlertsen B.; Albrechtsen A.; Bergsten E.; Bjerregaard P.; Hansen T.; Myrhøj T.; Nielsen P.B.; Timmermans-Wielenga V.; Andersen M.K.; Jønson L.; Nielsen F.C.
Breast Cancer Res Treat(2009)

124 The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects
Grarup N.; Andreasen C.H.; Andersen M.K.; Albrechtsen A.; Sandbæk A.; Lauritzen T.; Borch-Johnsen K.; Jørgensen T.; Schmitz O.; Hansen T.; Pedersen O.
J Clin Endocrinol Metab(2008)

125 The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes
Sparsø T.; Andersen G.; Nielsen T.; Burgdorf K.S.; Gjesing A.P.; Nielsen A.L.; Albrechtsen A.; Rasmussen S.S.; Jørgensen T.; Borch-Johnsen K.; Sandbæk A.; Lauritzen T.; Madsbad S.; Hansen T.; Pedersen O.
Diabetologia(2008)

126 Novel de novo BRCA2 mutation in a patient with a family history of breast cancer
Hansen T.V.O.; Bisgaard M.L.; Jønson L.; Albrechtsen A.; Filtenborg-Barnkob B.; Eiberg H.; Ejlertsen B.; Nielsen F.C.
BMC Medical Genetics(2008)

127 Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation
Andreasen C.H.; Stender-Petersen K.L.; Mogensen M.S.; Torekov S.S.; Wegner L.; Andersen G.; Nielsen A.L.; Albrechtsen A.; Borch-Johnsen K.; Rasmussen S.S.; Clausen J.O.; Sandbæk A.; Lauritzen T.; Hansen L.; Jørgensen T.; Pedersen O.; Hansen T.
Diabetes(2008)

128 Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 Loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged danes
Grarup N.; Andersen G.; Krarup N.T.; Albrechtsen A.; Schmitz O.; Joørgensen T.; Borch-Johnsen K.; Hansen T.; Pedersen O.
Diabetes(2008)

129 Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation
Sparsø T.; Andersen G.; Albrechtsen A.; Jørgensen T.; Borch-Johnsen K.; Sandbæk A.; Lauritzen T.; Wasson J.; Permutt M.A.; Glaser B.; Madsbad S.; Pedersen O.; Hansen T.
Diabetologia(2008)

130 Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects
Grarup N.; Andersen M.K.; Andreasen C.H.; Albrechtsen A.; Borch-Johnsen K.; Jørgensen T.; Auwerx J.; Schmitz O.; Hansen T.; Pedersen O.
J Clin Endocrinol Metab(2007)

131 A -243A→G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged white subjects
Boesgaard T.W.; Castella S.I.; Andersen G.; Albrechtsen A.; Sparsø T.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetic Medicine(2007)

132 A bayesian multilocus association method: Allowing for higher-order interaction in association studies
Albrechtsen A.; Castella S.; Andersen G.; Hansen T.; Pedersen O.; Nielsen R.
Genetics(2007)

133 Genetic analysis of the estrogen-related receptor α and studies of association with obesity and type 2 diabetes
Larsen L.H.; Rose C.S.; Sparsø T.; Overgaard J.; Torekov S.S.; Grarup N.; Jensen D.P.; Albrechtsen A.; Andersen G.; Ek J.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Int J Obes(2007)

134 Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: Validation and extension of genome-wide association studies
Grarup N.; Rose C.S.; Andersson E.A.; Andersen G.; Nielsen A.L.; Albrechtsen A.; Clausen J.O.; Rasmussen S.S.; Jørgensen T.; Sandbæk A.; Lauritzen T.; Schmitz O.; Hansen T.; Pedersen O.
Diabetes(2007)

135 Studies of associations between the Arg389Gly polymorphism of the β1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects
Gjesing A.P.; Andersen G.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetic Medicine(2007)

136 Variation in the peroxisome proliferator-activated receptor δ gene in relation to common metabolic traits in 7,495 middle-aged white people
Grarup N.; Albrechtsen A.; Ek J.; Borch-Johnsen K.; Jørgensen T.; Schmitz O.; Hansen T.; Pedersen O.
Diabetologia(2007)

137 A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4α gene (HNF4A) associates with late-onset diabetes
Ek J.; Hansen S.P.; Lajer M.; Nicot C.; Boesgaard T.W.; Pruhova S.; Johansen A.; Albrechtsen A.; Yderstræde K.; Lauenborg J.; Parrizas M.; Boj S.F.; Jørgensen T.; Borch-Johnsen K.; Damm P.; Ferrer J.; Lebl J.; Pedersen O.; Hansen T.
Diabetes(2006)

138 Large-scale study of the -232C > G polymorphism of PCK1 in Type 2 diabetes
Wegner L.; Andersen G.; Albrechtsen A.; Sparsø T.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetic Medicine(2006)

139 Variants in the 5′ region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects
Torekov S.S.; Larsen L.H.; Andersen G.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetologia(2006)

140 Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects
Grarup N.; Urhammer S.A.; Ek J.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetologia(2006)

141 Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes
Andersen G.; Overgaard J.; Albrechtsen A.; Glümer C.; Borch-Johnsen K.; Jørgensen T.; Hansen T.; Pedersen O.
Diabetologia(2006)